Protein Alignment VDAC3 and POR2

DIOPT Version :10

• Sequence 1: NP_001129166.1
• Gene: VDAC3 / 7419
• HGNCID: 12674
• Length: 284
• Species: Homo sapiens
• Sequence 2: NP_012152.3
• Gene: POR2 / 854692
• SGDID: S000001376
• Length: 281
• Species: Saccharomyces cerevisiae
• Alignment Length: 277
• Identity: 63/277 - (22%)
• Similarity: 122/277 - (44%)
• Gaps: 18/277 - (6%)

Human     9 DLGKAAKDVFNKG-YGFGMVKIDLKTKSCSGVMEFSTSGHAYTDTGKASGNLETKYKVCNYGLTF 72
            |:.:....:||:. :....:.:::.|.:.:|| .|:.........|....::|.::.....|::.
Yeast     8 DISRDVNGLFNRDFFHTNPLSLNISTTTENGV-NFTLKAKQGVTEGPIQTSVEGRFYDRKEGVSL 71

Human    73 TQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDI----D 133
            :|.|:..|.|.|.|.: :|:|.|.|..::....|.: .|:.|...||.:..|:..:::||    |
Yeast    72 SQSWSNQNRLNTRIEF-SKIAPGWKGDVNAFLTPQS-IKNAKFNLSYAQKSFAARTSIDILQPKD 134

Human   134 FSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQK 198
            |.|.     ..|...|::.|..:::|||....::...::||.|.::......|:......|.:|.
Yeast   135 FVGS-----VTLGHRGFVGGTDIAYDTAAGLCARYAMSIGYLAREYSFILSTNNRQCATASFFQN 194

Human   199 VNE--KIETSINLAWTAGSN-NTRFGIAAKYMLDCRTSLSAKVNNASLIGLGYTQTLRPGVKLTL 260
            ||.  ::.|...|.....|| |..|  ..:|:.|..:.:.||:.::.|..|.|.:.|...:.|.:
Yeast   195 VNRYLQVGTKATLQSKTSSNMNIEF--VTRYVPDSISQVKAKIADSGLTTLSYKRNLNKDISLGV 257

Human   261 SALIDGKNFSAGGHKVG 277
            ....:....:...||.|
Yeast   258 GMSFNALQLTEPVHKFG 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VDAC3	NP_001129166.1	Porin3_VDAC	5..283	CDD:132767	63/277 (23%)
POR2	NP_012152.3	Porin3_VDAC	6..280	CDD:132767	63/277 (23%)