Protein Alignment VDAC3 and Porin2

DIOPT Version :10

• Sequence 1: NP_001129166.1
• Gene: VDAC3 / 7419
• HGNCID: 12674
• Length: 284
• Species: Homo sapiens
• Sequence 2: NP_609462.1
• Gene: Porin2 / 34499
• FlyBaseID: FBgn0069354
• Length: 293
• Species: Drosophila melanogaster
• Alignment Length: 290
• Identity: 105/290 - (36%)
• Similarity: 162/290 - (55%)
• Gaps: 12/290 - (4%)

Human     4 TPTYCDLGKAAKDVFNKGYGFGMVKIDLKTKSCSGVMEFSTSGHAYTDTGKASGNLETKYKVCNY 68
            ||||.||||.|:|:|.:||..|:.:||.||.:.||: ||.|:|.|..|..|.:|:|::|||:.:.
  Fly     5 TPTYPDLGKLARDLFKRGYHPGIWQIDCKTLTNSGI-EFFTTGFASQDNSKVTGSLQSKYKIEDQ 68

Human    69 GLTFTQKWNTDNTLGTEISWENKLAEGLKLTLDTIFVPNTGKKSGKLKASYKRDCFSVGSNVDID 133
            |||.|::|||:|.|..||...:|||:||.|.::..|.|.:.:..||.|..|.:|.|:..:::.::
  Fly    69 GLTLTERWNTENWLFGEIMHRDKLAQGLMLAVEAKFQPGSNEADGKFKMGYAQDNFNFLADIGLN 133

Human   134 FSGPTIYGWAVLAFEGWLAGYQMSFDTAKSKLSQNNFALGYKAADFQLHTHVNDGTEFGGSIYQK 198
             |.|.:....|:..:.:|.|....||...::|.....|||:......||..:.:|..:..|::.|
  Fly   134 -SEPILNCSLVVGHKEFLGGVGTEFDVGNTELKGWKVALGWTNETATLHGELKNGDTWLASLFYK 197

Human   199 VNEKIETSINLAWTAGSNNTRFG----------IAAKYMLDCRTSLSAKVNNASLIGLGYTQTLR 253
            .:|||:..|.:...||......|          :...|.|:....:.|||||...:||||.|.||
  Fly   198 ASEKIDAGIEVTKGAGGGEAAEGEQQGGDVVVNLGMIYHLEEDALVRAKVNNLVELGLGYEQKLR 262

Human   254 PGVKLTLSALIDGKNFSAGGHKVGLGFELE 283
            .|:..::||::|..||..|.|:.|:|..|:
  Fly   263 DGITASISAVLDCNNFKDGNHRFGVGIALQ 292

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VDAC3	NP_001129166.1	Porin3_VDAC	5..283	CDD:132767	103/287 (36%)
Porin2	NP_609462.1	Porin3_VDAC	6..292	CDD:132767	103/287 (36%)