Protein Alignment VDAC2 and vdac-1

DIOPT Version :10

• Sequence 1: NP_001171712.1
• Gene: VDAC2 / 7417
• HGNCID: 12672
• Length: 309
• Species: Homo sapiens
• Sequence 2: NP_501211.1
• Gene: vdac-1 / 177524
• WormBaseID: WBGene00019900
• Length: 283
• Species: Caenorhabditis elegans
• Alignment Length: 281
• Identity: 116/281 - (41%)
• Similarity: 173/281 - (61%)
• Gaps: 5/281 - (1%)

Human    30 PPSYADLGKAARDIFNKGFGFGLVKLDVKTKSCSG--VEFSTSGSSNTDTGKVTGTLETKYKWCE 92
            ||::|||||:|:|:||||:.||.:|:|..|::...  |||.::.|.|..:||:.|.|:.|||..:
 Worm     3 PPTFADLGKSAKDLFNKGYNFGFLKIDSTTRAGDNKEVEFKSAASHNIGSGKLGGNLDVKYKIPQ 67

Human    93 YGLTFTEKWNTDNTLGTEIAIEDQICQGLKLTFDTTFSPNTGKKSGKIKSSYKRECINLGCDVDF 157
            ||:|.||||||:|.|||.|.:.:|..:|||:|.|:.::|:.||:|||:|..:......:..||..
 Worm    68 YGITLTEKWNTENQLGTVIEVNEQFGRGLKVTLDSLYAPHAGKRSGKVKLDWALPTARVTADVGV 132

Human   158 DFAGPAIHGSAVFGYEGWLAGYQMTFDSAKSKLTRNNFAVGYRTGDFQLHTNVNDGTEFGGSIYQ 222
            ..| |.|:.:.||..:|||.|...||||:.:||...:.|.|:.|..:.||:.|.:.|:||.|:|.
 Worm   133 TSA-PVINAAGVFSRDGWLIGAAATFDSSSNKLAATSLAFGHSTPQYTLHSFVINSTDFGASLYH 196

Human   223 KVCEDLDTSVNLAWTSGTNCTRFGIAAKYQLDPTASISAKVNNSSLIGVGYTQTLRPGVKLTLSA 287
            ||..:::....|.|..|.|...:.:|.||......::.||||:||.:.|..|.:|.|.:|||||.
 Worm   197 KVASNVEVGTQLGWKVGGNGADYALATKYAPSRDLTVRAKVNSSSQVAVAATHSLSPALKLTLST 261

Human   288 LVDGKSINAGGHKVGLALELE 308
            ..:..:.:|  ||.||.||.:
 Worm   262 QFNLAANDA--HKFGLGLEFD 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VDAC2	NP_001171712.1	Porin3_VDAC	30..308	CDD:132767	116/279 (42%)
vdac-1	NP_501211.1	Porin3_VDAC	3..280	CDD:132767	116/279 (42%)