Protein Alignment VDAC1 and porin

DIOPT Version :10

• Sequence 1: NP_001387957.1
• Gene: VDAC1 / 7416
• HGNCID: 12669
• Length: 297
• Species: Homo sapiens
• Sequence 2: NP_476813.1
• Gene: porin / 34500
• FlyBaseID: FBgn0004363
• Length: 282
• Species: Drosophila melanogaster
• Alignment Length: 294
• Identity: 163/294 - (55%)
• Similarity: 213/294 - (72%)
• Gaps: 14/294 - (4%)

Human     4 PPTYADLGKSARDVFTKGYGFGLIKLDLKTKSENGLEFTSSGSANTETTKVTGSLETKYRWTEYG 68
            ||:|:||||.|||:|:|||.|||.|||||||:.:|:||.::|.:|.|:.||.|||||||:..:||
  Fly     3 PPSYSDLGKQARDIFSKGYNFGLWKLDLKTKTSSGIEFNTAGHSNQESGKVFGSLETKYKVKDYG 67

Human    69 LTFTEKWNTDNTLGTEITVEDQLARGLKLTFDSSFSPNTGLSPCGREVVSCSLWKKNAKIKTGYK 133
            ||.||||||||||.||:.|:|||..||||:.:.:|:|.:|              .||.|.|..|.
  Fly    68 LTLTEKWNTDNTLFTEVAVQDQLLEGLKLSLEGNFAPQSG--------------NKNGKFKVAYG 118

Human   134 REHINLGCDMDFDIAGPSIRGALVLGYEGWLAGYQMNFETAKSRVTQSNFAVGYKTDEFQLHTNV 198
            .|::....|::.|:.||.|..:.||||:|||||||..|:|.:|::|.:|||:||.|.:|.|||.|
  Fly   119 HENVKADSDVNIDLKGPLINASAVLGYQGWLAGYQTAFDTQQSKLTTNNFALGYTTKDFVLHTAV 183

Human   199 NDGTEFGGSIYQKVNKKLETAVNLAWTAGNSNTRFGIAAKYQIDPDACFSAKVNNSSLIGLGYTQ 263
            |||.||.|||:|:.:.||:..|.|:|.:|.|||:|.|.||||:|.||...|||||:|.:||||.|
  Fly   184 NDGQEFSGSIFQRTSDKLDVGVQLSWASGTSNTKFAIGAKYQLDDDASVRAKVNNASQVGLGYQQ 248

Human   264 TLKPGIKLTLSALLDGKNVNAGGHKLGLGLEFQA 297
            .|:.|:.||||.|:||||.||||||:|:|||.:|
  Fly   249 KLRDGVTLTLSTLVDGKNFNAGGHKIGVGLELEA 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VDAC1	NP_001387957.1	Porin3_VDAC	4..296	CDD:132767	162/291 (56%)
porin	NP_476813.1	Porin3_VDAC	3..281	CDD:132767	162/291 (56%)