Protein Alignment VBP1 and mgr

DIOPT Version :10

• Sequence 1: NP_001290472.1
• Gene: VBP1 / 7411
• HGNCID: 12662
• Length: 233
• Species: Homo sapiens
• Sequence 2: NP_650067.1
• Gene: mgr / 41365
• FlyBaseID: FBgn0264694
• Length: 194
• Species: Drosophila melanogaster
• Alignment Length: 197
• Identity: 100/197 - (50%)
• Similarity: 141/197 - (71%)
• Gaps: 7/197 - (3%)

Human    37 MAAVKDSCGKGEMATGNGRRLHLGIPEAVFVEDVDSFMKQPGNETADTVLKKLDEQYQKYKFMEL 101
            |..:.||....::.  ..::...|||||||:|::|:||.||.||..:.||::||||:.||:||..
  Fly     1 MTGIMDSVEMPKLP--ENQKTFAGIPEAVFLEEIDTFMSQPENENCEKVLQRLDEQHGKYRFMAC 63

Human   102 NLAQKKRRLKGQIPEIKQTLEILKYMQKKKESTNSMETRFLLADNLYCKASVPPTDKVCLWLGAN 166
            ||..::|:||.|||:::::||::..::|:.|   ..||:|||:|.::.|..||||..|.|||||:
  Fly    64 NLEARRRKLKSQIPDLERSLEMVNVLRKEDE---ERETQFLLSDQVFIKTLVPPTKTVYLWLGAS 125

Human   167 VMLEYDIDEAQALLEKNLSTATKNLDSLEEDLDFLRDQFTTTEVNMARVYNWDVKRRNKDDSTKN 231
            |||||.:|||:|||.:|:::|..||.|:|.|.||||||.|||||||||||||.||:|..  :||.
  Fly   126 VMLEYPLDEAEALLNQNITSAVGNLKSVEHDQDFLRDQITTTEVNMARVYNWGVKKRQA--ATKT 188

Human   232 KA 233
            .|
  Fly   189 TA 190

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VBP1	NP_001290472.1	Prefoldin_3	88..216	CDD:467472	70/127 (55%)
		coiled coil	88..127	CDD:467472	18/38 (47%)
		coiled coil	174..216	CDD:467472	28/41 (68%)
mgr	NP_650067.1	Prefoldin_3	50..175	CDD:467472	70/127 (55%)
		coiled coil	50..89	CDD:467472	18/38 (47%)
		coiled coil	133..175	CDD:467472	28/41 (68%)