DRSC/TRiP Functional Genomics Resources

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Protein Alignment VARS1 and GstE8

DIOPT Version :9

Sequence 1:XP_005249419.1 Gene:VARS1 / 7407 HGNCID:12651 Length:1265 Species:Homo sapiens
Sequence 2:NP_001286571.1 Gene:GstE8 / 37113 FlyBaseID:FBgn0063492 Length:222 Species:Drosophila melanogaster


Alignment Length:176 Identity:39/176 - (22%)
Similarity:72/176 - (40%) Gaps:29/176 - (16%)


- Green bases have known domain annotations that are detailed below.


Human    53 PPPRLPALEQGPGGLWVWGATAV----------AQLLWPAGLGGPGGSRAAVLVQQWVSYADTEL 107
            |...:|.||.  .|.::|.:.|:          :..|:|..|     .:.||:.|:....:....
  Fly    51 PQHTVPTLED--DGHFIWDSHAISAYLVSKYGQSDTLYPKDL-----LQRAVVDQRLHFESGVVF 108

Human   108 IPAACGATLPALGLRSSAQD--PQAVLGALGRALSPLEEWLRLHTYLAGEAPTLADLAAVTALLL 170
            :....|.|.|   |.::.|.  |:....|:......:|.:|..|.::||:..|:||.:.:|::..
  Fly   109 VNGLRGITKP---LFATGQTTIPKERYDAVIEIYDFVETFLTGHDFIAGDQLTIADFSLITSITA 170

Human   171 PFRYVLDPPARRIWNNVTRWFVTCVRQPEFRAVLGEVVLYSGARPL 216
            ...:|:....:  :.|:|.|.......|.:....|:     |||.|
  Fly   171 LAVFVVIDTVK--YANITAWIKRIEELPYYEEACGK-----GARDL 209

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
VARS1XP_005249419.1 GstA <56..203 CDD:223698 33/158 (21%)
GST_C_ValRS_N 92..213 CDD:198327 25/122 (20%)
PTZ00419 283..1265 CDD:240411
ValRS_core 336..939 CDD:185677
tRNA-synt_1_2 514..>610 CDD:290334
Anticodon_Ia_Val 939..1076 CDD:153416
Val_tRNA-synt_C 1197..1259 CDD:287436
GstE8NP_001286571.1 GstA 4..196 CDD:223698 33/156 (21%)
GST_N_Delta_Epsilon 4..77 CDD:239343 7/27 (26%)
GST_C_Delta_Epsilon 91..209 CDD:198287 28/127 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0625
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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