DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment VARS1 and GstT3

DIOPT Version :9

Sequence 1:	XP_005249419.1	Gene:	VARS1 / 7407	HGNCID:	12651	Length:	1265	Species:	Homo sapiens
Sequence 2:	NP_001162808.1	Gene:	GstT3 / 33047	FlyBaseID:	FBgn0031117	Length:	268	Species:	Drosophila melanogaster

Alignment Length:	96	Identity:	25/96 - (26%)
Similarity:	37/96 - (38%)	Gaps:	22/96 - (22%)

- Green bases have known domain annotations that are detailed below.

Human   137 RALSPLEE-WLRLHTYLAGEAPTLADLAAVTAL----LLPFRYVLDPPARRIWNNVTRWFVTCVR 196
            |.|..:|| ||....:|.|.:.|:||:.|...:    :..:...:..|..|.|       :..||
  Fly   185 RNLDVVEEVWLEGKDFLTGSSLTVADIFAACEIEQTRMADYDVRIKYPKIRAW-------LKRVR 242

Human   197 Q---PEFRAVLGEVVLYSGARPLSHQPGPEA 224
            |   |.:......|...||.       ||:|
  Fly   243 QSCNPYYDVAHEFVYKISGT-------GPQA 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
VARS1	XP_005249419.1	GstA	<56..203	CDD:223698	19/73 (26%)
		GST_C_ValRS_N	92..213	CDD:198327	21/83 (25%)
		PTZ00419	283..1265	CDD:240411
		ValRS_core	336..939	CDD:185677
		tRNA-synt_1_2	514..>610	CDD:290334
		Anticodon_Ia_Val	939..1076	CDD:153416
		Val_tRNA-synt_C	1197..1259	CDD:287436
GstT3	NP_001162808.1	GST_N_Theta	45..121	CDD:239348
		GstA	47..243	CDD:223698	16/64 (25%)
		GST_C_Theta	135..259	CDD:198292	20/80 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900