Protein Alignment UVRAG and Uvrag

DIOPT Version :10

• Sequence 1: NP_001373600.1
• Gene: UVRAG / 7405
• HGNCID: 12640
• Length: 725
• Species: Homo sapiens
• Sequence 2: NP_001388471.1
• Gene: Uvrag / 308846
• RGDID: 1589754
• Length: 698
• Species: Rattus norvegicus
• Alignment Length: 725
• Identity: 620/725 - (85%)
• Similarity: 644/725 - (88%)
• Gaps: 27/725 - (3%)

Human     1 MSASASVGGPVPQPPPGPAAALPPGSAARALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTY 65
            ||:.||:|||||.|||||:|||.||:..|||||||||||||||||||||||||||||||||||||
  Rat     1 MSSCASLGGPVPLPPPGPSAALTPGAPTRALHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTY 65

Human    66 FTLHLCSTEKIYKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKENIYQLLIE 130
            ||||||..|||.|||||||||||||||||||||||||||||||||||||||||||||..||||||
  Rat    66 FTLHLCDNEKICKEFYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIWGGKEEAYQLLIE 130

Human   131 WKVCLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKTILLQVDQNCVRNSYDVFS 195
            |||.|||||||||||||||||||||||||||||||||||.:.||||. |||||||||||||||||
  Rat   131 WKVYLDGLKYLGQQIHARNQNEIIFGLNDGYYGAPFEHKAHPNAQKN-LLQVDQNCVRNSYDVFS 194

Human   196 LLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQNELERQKKALGR 260
            |||||||||||||||||||:||||||||||||||||||||:||||:||||||:||||||||||||
  Rat   195 LLRLHRAQCAIKQTQVTVQRIGKEIEEKLRLTSTSNELKKESECLRLKILVLRNELERQKKALGR 259

Human   261 EVALLHKQQIALQDKGSAFSAEHLKLQLQKESLNELRKECTAKRELFLKTNAQLTIRCRQLLSEL 325
            |||.|||||:|||||||||:|||.|||||||||.|||||||||||||||||||||||||||||||
  Rat   260 EVAFLHKQQMALQDKGSAFAAEHAKLQLQKESLRELRKECTAKRELFLKTNAQLTIRCRQLLSEL 324

Human   326 SYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKG 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   325 SYIYPIDLNEHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKG 389

Human   391 SRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLK 455
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   390 SRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLK 454

Human   456 NFMEHGLMVRCIKPQMSCFQFGAKPSWKRQPLTGNGCDRHHTSSAIPVPKRQSSIFGGADVGFSG 520
            ||||||||||                          |||||.||||||||||||.|.|||||.|.
  Rat   455 NFMEHGLMVR--------------------------CDRHHISSAIPVPKRQSSTFRGADVGLST 493

Human   521 GIPSPDKGHRKRASSENERLQYKTPPPSYNSALAQPVTTVPSMGETERKITSLSSSLDTSLDFSK 585
            |:||||..|||||||||||||||||||||||||.|....:|::|::|||:|.|||||||||||||
  Rat   494 GVPSPDNVHRKRASSENERLQYKTPPPSYNSALTQHGVAMPTLGDSERKVTPLSSSLDTSLDFSK 558

Human   586 ENKKKGEDLVGSLNGGHANVHPSQEQGEALSGHRATVNGTLLPSEQAGSASVQLPGEFHPVSEAE 650
            |:||.|.||..|::|.|.||..||||||||.||.||:|||.|||||.|.|...|||..||...||
  Rat   559 ESKKTGVDLGNSVSGDHRNVDSSQEQGEALPGHLATINGTALPSEQPGPAGTLLPGLCHPAPSAE 623

Human   651 LCCTVEQAEEIIGLEATGFASGDQLEAFNCIPVDSAVAVECDEQVLGEFEEFSRRIYALNENVSS 715
            |||.|||||||||||||||.|||||||.:||||||||||||||||||||||||||||||:|||||
  Rat   624 LCCAVEQAEEIIGLEATGFTSGDQLEALSCIPVDSAVAVECDEQVLGEFEEFSRRIYALSENVSS 688

Human   716 FRRPRRSSDK 725
            ||||||||||
  Rat   689 FRRPRRSSDK 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UVRAG	NP_001373600.1	VPS38	39..437	CDD:435943	377/397 (95%)
Uvrag	NP_001388471.1	VPS38	39..436	CDD:435943	377/397 (95%)