DRSC/TRiP Functional Genomics Resources

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Protein Alignment UVRAG and vps38

DIOPT Version :10

Sequence 1:NP_001373600.1 Gene:UVRAG / 7405 HGNCID:12640 Length:725 Species:Homo sapiens
Sequence 2:NP_595743.2 Gene:vps38 / 2540836 PomBaseID:SPBC18H10.19 Length:474 Species:Schizosaccharomyces pombe


Alignment Length:515 Identity:114/515 - (22%)
Similarity:203/515 - (39%) Gaps:152/515 - (29%)


- Green bases have known domain annotations that are detailed below.


Human    31 LHVELPSQQRRLRHLRNIAARNIVNRNGHQLLDTYFTLHLCSTEKIYKE---------------- 79
            :.:|||... ||..|::|..||:.....|    :.|.::  :||.::|.                
pombe     1 MSLELPGNY-RLSRLKSIQIRNVQEIQNH----SKFAIN--TTENLWKRDVQLKRAISEGTIRIF 58

Human    80 ------------------------FYRSEVIKNSLNPTWRSLDFGIMPDRLDTSVSCFVVKIW-G 119
                                    ||..|.:...|. .:|..::             |:|:.| .
pombe    59 ISLHVQSKKLPVYITETSGNANHIFYVDEKVTEKLQ-KYRHEEY-------------FIVRTWCS 109

Human   120 GKENIYQLLIEWKVCL--DGLKYLGQQ-----IHARNQNEIIFGLNDGYYGAPFEHKGYSNAQKT 177
            ...:.::|..|||:..  ...:|:|..     .|.|  |.::...|||.|       .|:.:|.:
pombe   110 SSSHAFKLHKEWKILRYDSNFRYIGNDPVFAVCHIR--NGLLCEFNDGVY-------IYTTSQSS 165

Human   178 ILLQVDQNCVRNSYDVFSLLRLHRAQCAIKQTQVTVQKIGKEIEEKLRLTSTSNELKKKSECLQL 242
            .:::  |.....|...:|:.|        ::...|:|||              ..:.|.:||:. 
pombe   166 DIMR--QTSFPKSASTYSIDR--------RKDGYTIQKI--------------TRILKLAECID- 205

Human   243 KILVLQNELER--QKKALGREVALLHKQQIALQDK-GSAFSAEHLKLQLQKESLNELR------- 297
            ::.:.::|:..  |::.. :::.|:||:.:...:| ......||| .|.|..|:.::|       
pombe   206 EMHIAKHEIRAHFQEEEF-QQIRLMHKRMLLRDEKIDELAKLEHL-WQKQINSITQMRTKFDKTK 268

Human   298 -------------KECTAKREL-------FLKTNAQLTIRCRQLL--------SELSYIYPIDLN 334
                         ||...|.|.       .|||..:..|..|.|:        |.||.||||..:
pombe   269 SWLSSKRNTLNKSKESLQKDEAEYVELANSLKTKVETNIEIRILMAHAIRMHVSHLSKIYPIQPS 333

Human   335 --EHKDYFVCGVKLPNSEDFQAKDDGSIAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKD 397
              .|.::.:..::|....|  ..::..:|.::|:.|||:..:|.:|:..|.|||:...|||:|.|
pombe   334 PGNHDEFTIRNLRLSFEPD--KINNVEMAASIGFLAHLLQTLSKYLEKELAYPILCASSRSSILD 396

Human   398 NINDKLTEKEREFPLYPKGGEKLQFDYGVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNF 457
            .:...:  ..|.|||||.......|::.:||||:::.......||   .:.|::..|:||
pombe   397 TLTPDI--PTRIFPLYPATRPIELFEHAIYLLNQDVNDFLETFGL---PIDQSMDILRNF 451

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
UVRAGNP_001373600.1 VPS38 39..437 CDD:435943 105/485 (22%)
vps38NP_595743.2 PRK12704 185..>311 CDD:237177 28/142 (20%)

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