Protein Alignment UVRAG and Y34B4A.2

DIOPT Version :10

• Sequence 1: NP_001373600.1
• Gene: UVRAG / 7405
• HGNCID: 12640
• Length: 725
• Species: Homo sapiens
• Sequence 2: NP_508896.3
• Gene: Y34B4A.2 / 189585
• WormBaseID: WBGene00021319
• Length: 339
• Species: Caenorhabditis elegans
• Alignment Length: 294
• Identity: 66/294 - (22%)
• Similarity: 119/294 - (40%)
• Gaps: 65/294 - (22%)

Human   213 VQKIGKEIEEKLRLTSTSNELKKKSECLQLKILVLQN------ELERQKKALGREVALLHKQQIA 271
            :|::.||::||.....|..|.....:.|.::..:.|:      |.|.:.|:...::.::.|..:|
 Worm    20 LQQVIKEVKEKETHLKTLRETIDDEDGLVVRYQMAQDLAIRVEEKEVKCKSYKTQIEMVQKLILA 84

Human   272 -------LQDKGSAFSAEHLKL-----------------QLQKESLNELRKECTAKRELFLKTNA 312
                   :|:|....:.:.:||                 :|:...:..:.....|.|:.|
 Worm    85 KRRIIYEVQEKIDKKNYDKMKLVEKTEGLGTQADNNVDTKLKNIKITRIMNRLVAYRKTF----- 144

Human   313 QLTIRCRQLLSELSYIYPIDL---------NEHKDYFVC-------GVKLPNSEDFQAK--DDGS 359
                    ||.|:..::.||:         |..:....|       |:.||:....|..  ::..
 Worm   145 --------LLQEIMDVFKIDIDGGPASMKQNRVRSDCKCVLVDTIRGLHLPHIASIQLSPHNERE 201

Human   360 IAVALGYTAHLVSMISFFLQVPLRYPIIHKGSRSTIKDNINDKLTEKEREFPLYPKGGEKLQFDY 424
            ...|:|....::.:||..|:..|||||:...|.|.:...|:||......    :.|..|:.:|..
 Worm   202 TTAAIGLLIQMLHVISRVLEYSLRYPIVPAASFSKVYCPIDDKWATLSG----WKKRSERERFLE 262

Human   425 GVYLLNKNIAQLRYQHGLGTPDLRQTLPNLKNFM 458
            |:..|.|||||||...|:.||...:||..|.:::
 Worm   263 GLSWLAKNIAQLRSDCGIPTPMADKTLSVLADWI 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UVRAG	NP_001373600.1	VPS38	39..437	CDD:435943	58/271 (21%)
Y34B4A.2	NP_508896.3	APG6	151..>244	CDD:461178	21/92 (23%)