Protein Alignment USF2 and hlh-30

DIOPT Version :9

• Sequence 1: XP_024307452.1
• Gene: USF2 / 7392
• HGNCID: 12594
• Length: 397
• Species: Homo sapiens
• Sequence 2: NP_001023411.1
• Gene: hlh-30 / 177157
• WormBaseID: WBGene00020930
• Length: 524
• Species: Caenorhabditis elegans
• Alignment Length: 371
• Identity: 75/371 - (20%)
• Similarity: 126/371 - (33%)
• Gaps: 131/371 - (35%)

Human    37 GGDGPGAEEQTAVAITSVQQAAFGDHNIQ--------------YQF-RTETNGG-------QVTY 79
            ||...||...:...:....|..||  |||              ::| .:.|.||       ::..
 Worm    95 GGGSSGAALSSPRKMQQTHQMLFG--NIQPPRGSPPSDGSDKIHRFGESPTPGGVGGVFGTELDD 157

Human    80 RVVQVTDGQLDGQGDTAGAVSVVSTAAFAGGQQAVTQV-GVDGAAQRPGPAAASVPPGPAAPFPL 143
            .::....|..|.|....||...::    .||::.::.. .:.||:.|.|...:..|
 Worm   158 LIIDELMGMEDDQRMRPGATRPMT----IGGEKTMSMARPIPGASSRAGSGHSGSP--------- 209

Human   144 AVIQNPFSNGGSPAAEAVSGEARFAYFPASSVGDTTAVSVQTTDQSLQAGGQFYVMMTPQDVLQT 208
            ..|.|..||.   ..:.||..|     |.||: |...:....::....:||.    ..|:|..
 Worm   210 ITIPNAMSNN---FRQVVSSSA-----PTSSI-DIEKMIGAVSNGGGNSGGD----NDPEDYY-- 259

Human   209 GTQRTIAPRTHPYSPKIDGTRTPRDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTG 273
                                   ||.|::..||.:|||||..||:.|.:|.:::|...:::.|.
 Worm   260 -----------------------RDRRKKDIHNMIERRRRYNINDRIKELGQMLPKNTSEDMKL- 300

Human   274 AVSTPDPQCLRWSRPPTLACRKSNSHGARESSLGWRPVGGACPKAPGPLAPQSKGGILSKACDYI 338
                                                                :||.||..:||||
 Worm   301 ----------------------------------------------------NKGTILKASCDYI 313

Human   339 RELRQTNQRMQETFKEAERLQMDNELLRQQIEELKNENALLRAQLQ 384
            |.|::..::..:|.::.:.|:........:::||  |..|.|..:|
 Worm   314 RVLQKDREQAMKTQQQQKSLESTAHKYADRVKEL--EEMLARQGVQ 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
USF2	XP_024307452.1	HLH	233..346	CDD:238036	25/112 (22%)
		ZapB	341..>385	CDD:310531	9/44 (20%)
hlh-30	NP_001023411.1	bHLHzip_MITF_like	260..328	CDD:381403	27/120 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1708
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940