Protein Alignment UQCRC1 and CG8728

DIOPT Version :10

• Sequence 1: NP_003356.2
• Gene: UQCRC1 / 7384
• HGNCID: 12585
• Length: 480
• Species: Homo sapiens
• Sequence 2: NP_610333.1
• Gene: CG8728 / 35748
• FlyBaseID: FBgn0033235
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 502
• Identity: 138/502 - (27%)
• Similarity: 222/502 - (44%)
• Gaps: 54/502 - (10%)

Human    18 LRARRSPALLRTPA---LRSTATFAQALQFVPE------------TQVSLLDNGLRVASEQSSQP 67
            :|....|..:.||:   :.......:.|..:||            |:|:.|.||||:|||.....
  Fly    49 VRTSDGPQKVNTPSKEIVTHLPPLTEPLPNLPEAVYAAPLAESAITKVTTLPNGLRIASEPRYGQ 113

Human    68 TCTVGVWIDVGSRFETEKNNGAGYFLEHLAFKGTKNRPG-SALEKEVESMGAHLNAYSTREHTAY 131
            .||||:.||.|.|:|....:|..:|||.|||..|.|.|. .|:.||:|..|...:..|:|:...|
  Fly   114 FCTVGLVIDSGPRYEVAYPSGVSHFLEKLAFNSTVNFPNKDAILKELEKNGGICDCQSSRDTLIY 178

Human   132 YIKALSKDLPKAVELLGDIVQNCSLEDSQIEKERDVILREMQENDASMR----DVVFNYLHATAF 192
            .....|:.:.....||.|:....:|.|.::...|..:..|::  ...||    .::.:.:||.||
  Fly   179 AASIDSRAIDSVTRLLADVTLRPTLSDQEVSLARRAVNFELE--TLGMRPEQEPILMDMIHAAAF 241

Human   193 QGTPLAQAVEGPSENVRKLSRADLTEYLSTHYKAPRMVLAAAGGVEHQQLLDLAQKHL---GGIP 254
            :...|......|.||:..::|..|..||..|:...|||:|.. ||:|.:|:...|::.   ..|.
  Fly   242 RDNTLGLPKLCPLENLDHINRNVLMNYLKYHHSPKRMVIAGV-GVDHDELVSHVQRYFVEDKAIW 305

Human   255 WTYA-EDAVP---TLTPCRFTGSEIRHRDD-------ALP-FAHVAIAVEGPGWASPDNVALQVA 307
            .|.| ||:.|   ..:..::||..::.:.:       .|| .|||.:..||......|.|.|.|.
  Fly   306 ETEALEDSGPKQVDTSIAQYTGGLVKEQCEIPIYAAAGLPELAHVILGFEGCSHQDKDFVPLCVL 370

Human   308 NAIIGHYDCTYGGGVHLSSPLASG-------AVANKL--CQSFQTFSICYAETGLLGAHFVCDRM 363
            |.::|      |||...:.....|       .|.|:.  ..|...::..|.:.||...|......
  Fly   371 NIMMG------GGGSFSAGGPGKGMYSRLYTKVLNRYHWMYSATAYNHAYGDCGLFCVHGSAPPQ 429

Human   364 KIDDMMFVLQGQWMRLCTSATESEVARGKNILRNALVSHLDGTTPVCEDIGRSLLTYGRRIPLAE 428
            .::||:.||..:.|.:.......|:.|.|..|::.|:.:|:....|.||:||.:|..|:|.....
  Fly   430 HMNDMVEVLTREMMGMAAEPGREELMRSKIQLQSMLLMNLESRPVVFEDVGRQVLVTGQRKRPQH 494

Human   429 WESRIAEVDASVVREICSKYIYDQCPAVAGYGPIEQLPDYNRIRSGM 475
            :...|..|.|:.::.:..: :....|:||..|.|..||:.:.|.:.:
  Fly   495 FIKEIESVTAADIQRVAQR-LLSSPPSVAARGDIHNLPEMSHITNAV 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UQCRC1	NP_003356.2	PqqL	35..466	CDD:440377	131/471 (28%)
CG8728	NP_610333.1	PqqL	79..521	CDD:440377	126/451 (28%)