Protein Alignment UPP1 and CG6330

DIOPT Version :10

• Sequence 1: NP_003355.1
• Gene: UPP1 / 7378
• HGNCID: 12576
• Length: 310
• Species: Homo sapiens
• Sequence 2: NP_733175.1
• Gene: CG6330 / 43240
• FlyBaseID: FBgn0039464
• Length: 368
• Species: Drosophila melanogaster
• Alignment Length: 304
• Identity: 154/304 - (50%)
• Similarity: 212/304 - (69%)
• Gaps: 1/304 - (0%)

Human     6 ANAEKAESHNDCPVRLLNPNIAKMKEDILYHFNLTTSRHNFPALFGDVKFVCVGGSPSRMKAFIR 70
            |..::...::|..|:|.|.||..|.:|||||..|.:..|:...:||||||||:||:|.||:.|..
  Fly    33 AYVKRITRYSDGTVKLRNSNIELMDQDILYHLALGSESHDLQEMFGDVKFVCMGGTPKRMENFAH 97

Human    71 CVGAELGLDCP-GRDYPNICAGTDRYAMYKVGPVLSVSHGMGIPSISIMLHELIKLLYYARCSNV 134
            .:..|:|...| |....:|.|.:.||:||||||||.||||||.||:||::||:|||:|:|:|.:.
  Fly    98 FIMNEIGYKLPAGTQLQDISAYSYRYSMYKVGPVLCVSHGMGTPSVSILMHEMIKLMYHAKCKDP 162

Human   135 TIIRIGTSGGIGLEPGTVVITEQAVDTCFKAEFEQIVLGKRVIRKTDLNKKLVQELLLCSAELSE 199
            ..|||||.||||::.|||:|||.|:|...:...|..:|||.:.|...|:|||.:||...::....
  Fly   163 VFIRIGTCGGIGVDGGTVIITEDALDGQLRNSHEFTILGKTIHRPAKLDKKLARELKSLASPDDP 227

Human   200 FTTVVGNTMCTLDFYEGQGRLDGALCSYTEKDKQAYLEAAYAAGVRNIEMESSVFAAMCSACGLQ 264
            :.|::|.|:||.||||||||||||.|.::|.:|.||||.....||.||||||::|||:....|::
  Fly   228 YDTIIGKTLCTNDFYEGQGRLDGAFCDFSENEKMAYLEKLRENGVVNIEMESTIFAALTHHAGIK 292

Human   265 AAVVCVTLLNRLEGDQISSPRNVLSEYQQRPQRLVSYFIKKKLS 308
            ||||||.|||||.|||:::|:.|::|:|.|||.|||.:|:|.|:
  Fly   293 AAVVCVALLNRLNGDQVNAPKEVMNEWQARPQILVSRYIRKVLT 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
UPP1	NP_003355.1	UP_hUPP-like	31..305	CDD:350163	144/274 (53%)
CG6330	NP_733175.1	UP_hUPP-like	59..333	CDD:350163	144/273 (53%)