| Sequence 1: | NP_001365163.1 | Gene: | UMOD / 7369 | HGNCID: | 12559 | Length: | 687 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_058778.2 | Gene: | Umod / 25128 | RGDID: | 3940 | Length: | 644 | Species: | Rattus norvegicus |
| Alignment Length: | 689 | Identity: | 499/689 - (72%) |
|---|---|---|---|
| Similarity: | 556/689 - (80%) | Gaps: | 53/689 - (7%) |
- Green bases have known domain annotations that are detailed below.
|
Human 1 MGQ-PSLTWMLMV-VVASWFITTAATDTSEARWCSECHSNATCTEDEAVTTCTCQEGFTGDGLTC 63
Human 64 VDLDECAIPGAHNCSANSSCVNTPGSFSCVCPEGFRLSPGLGCTDVDECAEPGLSHCHALATCVN 128
Human 129 VVGSYLCVCPAGYRGDGWHCECSPGSCGPGLDCVPEGDA--LVCADPCQAHRTLDEYWRSTEYGE 191
Human 192 GYACDTDLRGWYRFVGQGGARMAETCVPVLRCNTAAPMWLNGTHPSSDEGIVSRKACAHWSGHCC 256
Human 257 LWDASVQVKACAGGYYVYNLTAPPECHLAYCTDPSSVEGTCEECSIDEDCKSNNGRWHCQCKQDF 321
Human 322 NITDISLLEHRLECGANDMKVSLGKCQLKSLGFDKVFMYLSDSRCSGFNDRDNRDWVSVVTPARD 386
Human 387 GPCGTVLTRNETHATYSNTLYLADEIIIRDLNIKINFACSYPLDMKVSLKTALQPMVSQTQERML 451
Human 452 GTDEGAQLTWRKKSAHCKLLAGTSPGLAVSWSNVAPSSACALNIRVGGTGMFTVRMALFQTPSYT 516
Human 517 QPYQGSSVTLSTEAFLYVGTMLDGGDLSRFALLMTNCYATPSSNATDPLKYFIIQDRCPHTRDST 581
Human 582 IQVVENGESSQGRFSVQMFRFAGNYDLVYLHCEVYLCDTMNEKCKPTCSGTRFRSGSVIDQSRVL 646
Human 647 NLGPITRKGVQATVSRAFSS-LGLLKVWLPLLLSATLTL 684 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| UMOD | NP_001365163.1 | EGF_3 | 35..63 | CDD:403986 | 20/27 (74%) |
| EGF_CA | 65..103 | CDD:311536 | 23/37 (62%) | ||
| EGF_CA | 108..149 | CDD:214542 | 30/40 (75%) | ||
| ZP | 334..630 | CDD:214579 | 207/295 (70%) | ||
| Umod | NP_058778.2 | EGF_3 | 37..65 | CDD:403986 | 20/27 (74%) |
| EGF_CA | 67..108 | CDD:214542 | 27/41 (66%) | ||
| EGF_3 | 120..149 | CDD:403986 | 22/28 (79%) | ||
| ZP | 337..586 | CDD:214579 | 207/295 (70%) | ||
| ZP-N. /evidence=ECO:0000255 | 337..432 | 73/94 (78%) | |||
| Flexible linker, important for secretion and polymerization into filaments. /evidence=ECO:0000250|UniProtKB:P07911 | 433..456 | 19/69 (28%) | |||
| Internal hydrophobic patch (IHP). /evidence=ECO:0000255 | 457..467 | 7/9 (78%) | |||
| ZP-C. /evidence=ECO:0000255 | 468..592 | 107/123 (87%) | |||
| Essential for cleavage by HPN. /evidence=ECO:0000250|UniProtKB:P07911 | 589..592 | 1/2 (50%) | |||
| Regulates polymerization into filaments. /evidence=ECO:0000250|UniProtKB:P07911 | 601..610 | 8/8 (100%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C83690436 | |
| Domainoid | 1 | 1.000 | 443 | 1.000 | Domainoid score | I9242 |
| eggNOG | 1 | 0.900 | - | - | E1_28KQA | |
| HGNC | 1 | 1.500 | - | - | ||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 1 | 1.000 | - | - | H2522 | |
| Inparanoid | 1 | 1.050 | 1077 | 1.000 | Inparanoid score | I4866 |
| NCBI | 1 | 1.000 | - | - | ||
| OMA | 1 | 1.010 | - | - | QHG38122 | |
| OrthoDB | 1 | 1.010 | - | - | D110098at40674 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001512 | |
| OrthoInspector | 1 | 1.000 | - | - | oto136683 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_117283 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR14002 |
| Phylome | 1 | 0.910 | - | - | ||
| SonicParanoid | 1 | 1.000 | - | - | X726 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 16 | 16.310 | |||||