Protein Alignment CG42340 and KCNK6

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_004814.1
• Gene: KCNK6 / 9424
• HGNCID: 6281
• Length: 313
• Species: Homo sapiens
• Alignment Length: 451
• Identity: 101/451 - (22%)
• Similarity: 156/451 - (34%)
• Gaps: 158/451 - (35%)

  Fly    98 GVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDRLWSITEDL 162
            |.|.....|..:|:::...|||                  |......||:            |.|
Human     9 GALAAYAAYLVLGALLVARLEG------------------PHEARLRAEL------------ETL 43

  Fly   163 NILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGI-QLNAPTHKWTYASAFLYSLTLITTIG 226
            .....:....:||..:..|.:.:|.|.|..:|...... ..||....|.:|||..::.|||||:|
Human    44 RAQLLQRSPCVAAPALDAFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVG 108

  Fly   227 YGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGGASGG 291
            ||..:|.|..|:..::.:||.|:|..:|.|:|..:.||..:.
Human   109 YGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSLLLT----------------------- 150

  Fly   292 VGSGAGGSGGGRKTDKNKGQGHYGHQKLH----QYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQ 352
                                    |..|.    ::|..|
Human   151 ------------------------HVPLSWLSMRWGWDP-------------------------- 165

  Fly   353 QQQVQQGKKSSGNRRGSPSVPISIC-VCVLLCYVSSGAILFHKLQNWSVLESLYFCFTSLGTIGF 416
                         ||.:....:::. |.|.:|::....|..|..:.||.|::.||||.||.|||.
Human   166 -------------RRAACWHLVALLGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGL 217

  Fly   417 GEMAPNGAV-----ALYTASAYILVGMAVVAMCFSLIQTEIVLWLRRFSVQDHVMPKAEELALVT 476
            |:..|..|.     |||.....:.:.:.:|||         ||.|:.|.   ||   ::...|..
Human   218 GDYVPGEAPGQPYRALYKVLVTVYLFLGLVAM---------VLVLQTFR---HV---SDLHGLTE 267

  Fly   477 VAVTPKPSXQRPSADPSLGVGLGVGLAGGALG-QPQNNLGQHQTMFFGPAHTLTQYSSLPR 536
            :.:.|.|.....:||....|.:        || ||::    ||.:   .|.:.|.|:|:||
Human   268 LILLPPPCPASFNADEDDRVDI--------LGPQPES----HQQL---SASSHTDYASIPR 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	22/55 (40%)
		Ion_trans_2	380..453	CDD:400301	25/77 (32%)
KCNK6	NP_004814.1	Ion_trans_2	<91..146	CDD:285168	22/54 (41%)
		Ion_trans_2	180..256	CDD:285168	28/84 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	288..313		10/39 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155148
Domainoid	1	1.000	57	1.000	Domainoid score	I10857
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.740