DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42340 and TOK1

DIOPT Version :9

Sequence 1:	NP_001368973.1	Gene:	CG42340 / 7354472	FlyBaseID:	FBgn0259242	Length:	759	Species:	Drosophila melanogaster
Sequence 2:	NP_012442.1	Gene:	TOK1 / 853352	SGDID:	S000003629	Length:	691	Species:	Saccharomyces cerevisiae

Alignment Length:	242	Identity:	45/242 - (18%)
Similarity:	93/242 - (38%)	Gaps:	60/242 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 TYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQ 274
            ||.:|..:....:.|:|.|.|.|::...::..|:::|.|:.::.|.:......:......:|...
Yeast   273 TYGNALYFCTVSLLTVGLGDILPKSVGAKIMVLIFSLSGVVLMGLIVFMTRSIIQKSSGPIFFFH 337

  Fly   275 RVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQ 339
            ||:.|                           ::|...||.....:        ..:::|....:
Yeast   338 RVEKG---------------------------RSKSWKHYMDSSKN--------LSEREAFDLMK 367

  Fly   340 AQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVLESL 404
            ..:|.|.:.|.                    ...:|:.:.:.:.:...||::|...:|||....:
Yeast   368 CIRQTASRKQH--------------------WFSLSVTIAIFMAFWLLGALVFKFAENWSYFNCI 412

  Fly   405 YFCFTSLGTIGFGEMAP-NGAVALYTASAYILVGMAVVAMCFSLIQT 450
            ||||..|.|||:|:.|| .||...:    :::..:..|.:..:::.|
Yeast   413 YFCFLCLLTIGYGDYAPRTGAGRAF----FVIWALGAVPLMGAILST 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	12/53 (23%)
CG42340	NP_001368973.1	Ion_trans_2	380..453	CDD:400301	21/72 (29%)
TOK1	NP_012442.1	Ion_trans_2	253..328	CDD:400301	12/54 (22%)
TOK1	NP_012442.1	Ion_trans_2	388..462	CDD:400301	21/72 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157345203
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840