Protein Alignment CG42340 and KCNK16

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_001128577.1
• Gene: KCNK16 / 83795
• HGNCID: 14464
• Length: 322
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 79/358 - (22%)
• Similarity: 133/358 - (37%)
• Gaps: 148/358 - (41%)

  Fly    82 LCGC---QKAPKSHCISATGVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELA 143
            ||.|   :..|         :||..:.|..:|:.:|..||.:
Human     6 LCSCWGGRVLP---------LLLAYVCYLLLGATIFQLLERQ----------------------- 38

  Fly   144 NAEIRSRTVDRLWSITEDLNILYKENWTRL----AAQEVQLFQDTLLRAVRQSKVYPPGGIQLNA 204
             ||.:||...:|    |.|..|  ||:|.|    ..|.||:..:..::.|.      |.|...|
Human    39 -AEAQSRDQFQL----EKLRFL--ENYTCLDQWAMEQFVQVIMEAWVKGVN------PKGNSTN- 89

  Fly   205 PTHKWTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRC 269
            |:: |.:.|:|.::.|::||||||.::|.|:.|:|..:.|||.|||:.:::|:.:|..|.|.:..
Human    90 PSN-WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAA 153

  Fly   270 LFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQA 334
            :   :|.:..|                      |::           |.|...||
Human   154 I---ERWEDRP----------------------RRS-----------QVLQVLGL---------- 172

  Fly   335 QQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWS 399
                                                ::.:::...|:|.:   ..::|..::.||
Human   173 ------------------------------------ALFLTLGTLVILIF---PPMVFSHVEGWS 198

  Fly   400 VLESLYFCFTSLGTIGFGE---------MAPNG 423
            ..|..||.|.:|.|||||:         :.|:|
Human   199 FSEGFYFAFITLSTIGFGDYVVGHPLNFITPSG 231

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	22/55 (40%)
		Ion_trans_2	380..453	CDD:400301	17/53 (32%)
KCNK16	NP_001128577.1	Ion_trans_2	<92..148	CDD:311712	22/56 (39%)
		Ion_trans_2	180..>224	CDD:311712	15/46 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155154
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840