Protein Alignment CG42340 and Kcnk16

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_083282.1
• Gene: Kcnk16 / 74571
• MGIID: 1921821
• Length: 292
• Species: Mus musculus
• Alignment Length: 406
• Identity: 95/406 - (23%)
• Similarity: 157/406 - (38%)
• Gaps: 146/406 - (35%)

  Fly    82 LCGC---QKAPKSHCISATGVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELA 143
            :|||   |..|         :||..:.|..:|:.:|..||.:
Mouse     6 VCGCWGGQVLP---------LLLAYICYLLLGATIFQLLEKQ----------------------- 38

  Fly   144 NAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHK 208
             ||.:||...:|    |.|..|  ||:|.|..|.::.|...:|.|  ..|...|.|...| |::
Mouse    39 -AEAQSRDQFQL----EKLRFL--ENYTCLDQQALEQFVQVILEA--WVKGVNPKGNSTN-PSN- 92

  Fly   209 WTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRR 273
            |.:.|:|.::.|::||||||.::|.|:.|:|..:.|||.|||:.:::|:.:|..|.|.:
Mouse    93 WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALMGIPLNVVFLNHLGTGLRAHL------ 151

  Fly   274 QRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQ-YGLPPSVYQQQQAQQA 337
                                           |..::.:.|..|.:|.| .||
Mouse   152 -------------------------------TTLDRWEDHPRHSQLLQVLGL------------- 172

  Fly   338 QQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVLE 402
                                             ::.:::...|:|.:   ..:.|..::.||..|
Mouse   173 ---------------------------------ALFLTLGTLVILIF---PPMFFSHVEGWSFRE 201

  Fly   403 SLYFCFTSLGTIGFGEMA-----PNGAVALY--TASAYILVGMAVVAMCFS----LIQTEIVLW- 455
            ..||.|.:|.|||||:..     ....:|:|  .|:.:||:|:|.:|:..|    |:.....||
Mouse   202 GFYFAFITLSTIGFGDYVVGTDPSKHYIAVYRSLAAIWILLGLAWLAVVLSLGSLLLHRCSRLWQ 266

  Fly   456 -LRRFSVQDHVMPKAE 470
             :|...::|...|.:|
Mouse   267 LIRGLDLKDGAAPDSE 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	22/55 (40%)
		Ion_trans_2	380..453	CDD:462301	25/83 (30%)
Kcnk16	NP_083282.1	Ion_trans_2	87..145	CDD:462301	23/59 (39%)
		Selectivity filter 1. /evidence=ECO:0000250|UniProtKB:Q96T55	108..113		4/4 (100%)
		Ion_trans_2	180..248	CDD:462301	22/70 (31%)
		Selectivity filter 2. /evidence=ECO:0000250|UniProtKB:Q96T55	212..217		4/4 (100%)