Protein Alignment CG42340 and Kcnk12

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: XP_038968799.1
• Gene: Kcnk12 / 64119
• RGDID: 68940
• Length: 521
• Species: Rattus norvegicus
• Alignment Length: 489
• Identity: 83/489 - (16%)
• Similarity: 147/489 - (30%)
• Gaps: 221/489 - (45%)

  Fly    83 CGCQKAPKSHCISATG--VLL--LVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELA 143
            |.|....:||....||  |||  |:.||...|:.||..||...|
  Rat    22 CCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGE--------------------- 65

  Fly   144 NAEIRSRTVDRLWSITEDLNILYKENWTR---LAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAP 205
             ||.|:|     |..|       ..|::.   :|..|::.|       :|..:.....|::.:|.
  Rat    66 -AEARAR-----WGAT-------LRNFSAAHGVAEPELRAF-------LRHYEAALAAGVRADAL 110

  Fly   206 THKWTYASAFLYSLTLITTI--------------------------------------------- 225
            ..:|.:..||.:..|:::||
  Rat   111 RPRWDFPGAFYFVGTVVSTIDSQIPTAAVCRHPKADQFMHPRPCVQLLGLSQSRSLATMLLKFQS 175

  Fly   226 ----------------------------------------------GYGGISPRTQWGRVAALVY 244
                                                          |:|..:|.|..|:...:.|
  Rat   176 SKLSTITPSTHWAFPVTPPLARGRGTSFRRRCCGCTWRLGLSVACPGFGMTTPATVGGKAFLIAY 240

  Fly   245 ALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNK 309
            .|||....:|:.:...|.:.:.:..:.|..|
  Rat   241 GLFGCAGTILFFNLFLERIISLLAFIMRACR---------------------------------- 271

  Fly   310 GQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSV-- 372
                  .::|.:.||.|:.:::..|                     :.:....:|   ..|||
  Rat   272 ------ERQLRRSGLLPATFRRGSA---------------------LSEADSLAG---WKPSVYH 306

  Fly   373 ---PISICVCVLLCYVSSGAILFHKLQNWSVLESLYFCFTSLGTIGFGEMAPNGAVALYTASAY- 433
               .:.:...:|.|..|:   ::..::.|..::||||||.:..|||||::..:...|......|
  Rat   307 VLLILGLFAVLLACCASA---MYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQGLYR 368

  Fly   434 ------ILVGMAVVAMCFSLIQ---TEIVLWLRR 458
                  ||:|:..:...|::|.   .:::.|:.|
  Rat   369 LGNFLFILLGVCCIYSLFNVISILIKQVLNWMLR 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	17/146 (12%)
		Ion_trans_2	380..453	CDD:462301	22/82 (27%)
Kcnk12	XP_038968799.1	Ion_trans_2	313..395	CDD:462301	22/84 (26%)