Protein Alignment CG42340 and KCNK15

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_071753.2
• Gene: KCNK15 / 60598
• HGNCID: 13814
• Length: 330
• Species: Homo sapiens
• Alignment Length: 535
• Identity: 112/535 - (20%)
• Similarity: 163/535 - (30%)
• Gaps: 246/535 - (45%)

  Fly    94 ISATGVLLLVLLYTAMGSIVFVTLEGELEDG---------GALETAVAASKPYPRTELANAEIRS 149
            :.|.|::|..|.|..:|:.||..||.|.|.|         |||......|
Human     6 VRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFS--------------- 55

  Fly   150 RTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHKWTYASA 214
                     .||    |:|                |.|...|::.:..|        .:|.:..:
Human    56 ---------AED----YRE----------------LERLALQAEPHRAG--------RQWKFPGS 83

  Fly   215 FLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGG 279
            |.:::|:||||.||..:|.|..|:|..:.|||.|||:.|:...::||.|:|.:|.|
Human    84 FYFAITVITTIEYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVVRRL--------- 139

  Fly   280 PGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQ 344
                                                                             
Human   140 ----------------------------------------------------------------- 139

  Fly   345 AQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLC--YVSSGAILFHKLQNWSVLESLYFC 407
                       :...|...|.|....|....:...:|.|  .::.||:.|...:.|:...:.|:|
Human   140 -----------LLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYC 193

  Fly   408 FTSLGTIGFGEMAPNGAVALYTASA-------------YILVGMAVVAMCFSLIQTEIVLWLRRF 459
            |.:|.|||||:.     |||.:..|             |||:|:.|:....:|:       :.||
Human   194 FITLTTIGFGDF-----VALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLNLV-------VLRF 246

  Fly   460 SVQDHVMPKAEELALVTVAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQPQNNLGQHQTMFFGP 524
            .|.....|:       ..|.||.|  :.|.|..|.|:.
Human   247 LVASADWPE-------RAARTPSP--RPPGAPESRGLW--------------------------- 275

  Fly   525 AHTLTQYSSLPRRSHLQAANNSGGGSAFQRNTPIRRSTGIPEHHLEYFVPRSISEFNLSGVGDLA 589
                     ||||    .|.:.|..|.|           ...|.||    |...:       :|.
Human   276 ---------LPRR----PARSVGSASVF-----------CHVHKLE----RCARD-------NLG 305

  Fly   590 LPPPRRYSPNMVGGG 604
            ..||.  ||.:|.||
Human   306 FSPPS--SPGVVRGG 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	22/55 (40%)
		Ion_trans_2	380..453	CDD:462301	25/87 (29%)
KCNK15	NP_071753.2	Ion_trans_2	<73..132	CDD:462301	23/66 (35%)
		Ion_trans_2	177..243	CDD:462301	21/77 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	256..276		8/57 (14%)