Protein Alignment CG42340 and KCNK13

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_071337.2
• Gene: KCNK13 / 56659
• HGNCID: 6275
• Length: 408
• Species: Homo sapiens
• Alignment Length: 505
• Identity: 108/505 - (21%)
• Similarity: 177/505 - (35%)
• Gaps: 167/505 - (33%)

  Fly   102 LVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELAN-AEIRSRTVDRLWSITEDLNIL 165
            |::||...|:.||..|                       |||: .:.:.|..:||.:.:...|
Human    26 LIVLYLLGGAAVFSAL-----------------------ELAHERQAKQRWEERLANFSRGHN-- 65

  Fly   166 YKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHKWTYASAFLYSLTLITTIGYGGI 230
                          |.:|.|...:|..:.....||:::....:|.:..||.:..|:::|||:|..
Human    66 --------------LSRDELRGFLRHYEEATRAGIRVDNVRPRWDFTGAFYFVGTVVSTIGFGMT 116

  Fly   231 SPRTQWGRVAALVYALFGIPIVLLYLSAMGEAL---------SAGMRCLFRRQRVKGGPGGGPGG 286
            :|.|..|::..:.|.|.|....:|:.:...|.|         |...|.|.||       |..|
Human   117 TPATVGGKIFLIFYGLVGCSSTILFFNLFLERLITIIAYIMKSCHQRQLRRR-------GALP-- 172

  Fly   287 GASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQA 351
                            :::.|:.||.......    |..||||.
Human   173 ----------------QESLKDAGQCEVDSLA----GWKPSVYY--------------------- 196

  Fly   352 QQQQVQQGKKSSGNRRGSPSVPISICVCVLL--CYVSSGAILFHKLQNWSVLESLYFCFTSLGTI 414
                                |.:.:|...:|  |..|:   ::..::.||..:||||||.:..||
Human   197 --------------------VMLILCTASILISCCASA---MYTPIEGWSYFDSLYFCFVAFSTI 238

  Fly   415 GFGEM-----APNGAVALYTAS--AYILVGMAVVAMCFSLIQTEI---VLWLRRFSVQDHVMPKA 469
            |||::     |...:..||..:  .:||:|:..:...|::|...|   :.|:.| .:.....|:.
Human   239 GFGDLVSSQNAHYESQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILR-KMDSGCCPQC 302

  Fly   470 EELALVTVAVTPKPSXQRPSADPSL---GVGL----GVGLAG-------------GALGQPQNNL 514
            :...|.:......|...|...:.|:   ||..    |..|:|             .:|...|..|
Human   303 QRGLLRSRRNVVMPGSVRNRCNISIETDGVAESDTDGRRLSGEMISMKDLLAANKASLAILQKQL 367

  Fly   515 GQHQTMFFGPAHTLTQYSSLPRRSHLQAANNSGGGSAFQ-RNTPIRRSTG 563
            .:   |..|..|   |.|:|.|.:..     |||..||. .|..:..::|
Human   368 SE---MANGCPH---QTSTLARDNEF-----SGGVGAFAIMNNRLAETSG 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	17/64 (27%)
		Ion_trans_2	380..453	CDD:400301	25/84 (30%)
KCNK13	NP_071337.2	Ion_trans_2	<94..150	CDD:311712	16/55 (29%)
		Ion_trans_2	206..285	CDD:311712	25/81 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155142
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4404
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740