Protein Alignment CG42340 and KCNK10

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_612190.1
• Gene: KCNK10 / 54207
• HGNCID: 6273
• Length: 543
• Species: Homo sapiens
• Alignment Length: 496
• Identity: 108/496 - (21%)
• Similarity: 179/496 - (36%)
• Gaps: 173/496 - (34%)

  Fly    79 GGSLCGCQKAPKSHCISATGVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELA 143
            |.|..|.|...|...:.|  :.::|::|...|.:||..||...|  .:.:..:|..|
Human    62 GTSQGGLQTVMKWKTVVA--IFVVVVVYLVTGGLVFRALEQPFE--SSQKNTIALEK-------- 114

  Fly   144 NAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHK 208
             ||                   :..:...::.||::......|.|  .:....|.|...|..:|
Human   115 -AE-------------------FLRDHVCVSPQELETLIQHALDA--DNAGVSPIGNSSNNSSH- 156

  Fly   209 WTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRR 273
            |...|||.::.|:|||||||.|:|.|:.|::..::||:||||:....|:.:|:.|..    :|.:
Human   157 WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQLGT----IFGK 217

  Fly   274 Q--RVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQ 336
            .  ||:                                                 .|::::|..|
Human   218 SIARVE-------------------------------------------------KVFRKKQVSQ 233

  Fly   337 AQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVL 401
            .:                           .|...::...:..|::  :|:..|::|..::.|:.|
Human   234 TK---------------------------IRVISTILFILAGCIV--FVTIPAVIFKYIEGWTAL 269

  Fly   402 ESLYFCFTSLGTIGFGEMAPNGAVALYTASAY-------ILVGMAVVAMCFSLIQTEIVLWLRRF 459
            ||:||...:|.|:|||:....|...:.....|       ||||:|..|...|:|..    |||..
Human   270 ESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMIGD----WLRVL 330

  Fly   460 S---------VQDHVMPKAEELALVT---------VAVTPKPSXQRPSADPSLGVGLGVGLAGGA 506
            |         ::.|.   ||..|.||         ::|......||.:...|:
Human   331 SKKTKEEVGEIKAHA---AEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSM------------ 380

  Fly   507 LGQPQNNLGQHQTMFFGPAHTLTQYSSLPRRSHLQAANNSG 547
               .:..||..|.     ||:|...|  |.:..:.||.::|
Human   381 ---ERRRLGLDQR-----AHSLDMLS--PEKRSVFAALDTG 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	24/55 (44%)
		Ion_trans_2	380..453	CDD:400301	24/79 (30%)
KCNK10	NP_612190.1	Ion_trans_2	153..211	CDD:285168	25/58 (43%)
		Ion_trans_2	249..328	CDD:285168	26/84 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155145
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840