Sequence 1: | NP_001368973.1 | Gene: | CG42340 / 7354472 | FlyBaseID: | FBgn0259242 | Length: | 759 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_002236.1 | Gene: | KCNK1 / 3775 | HGNCID: | 6272 | Length: | 336 | Species: | Homo sapiens |
Alignment Length: | 418 | Identity: | 90/418 - (21%) |
---|---|---|---|
Similarity: | 146/418 - (34%) | Gaps: | 160/418 - (38%) |
- Green bases have known domain annotations that are detailed below.
Fly 81 SLCG--CQKAPKSH----CISATGVLLL-VLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYP 138
Fly 139 RTELANAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQL- 202
Fly 203 -NAPTH-KWTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSA 265
Fly 266 GMRCLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQ 330
Fly 331 QQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLL------CYVSSGA 389
Fly 390 ILFHKLQ-NWSVLESLYFCFTSLGTIGFGEMAPNGAV-----ALYT--ASAYILVG---MAVVAM 443
Fly 444 CFSLIQTEIVLWLRRFSVQDHVMPKAEE 471 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
CG42340 | NP_001368973.1 | Ion_trans_2 | <208..264 | CDD:400301 | 18/55 (33%) |
Ion_trans_2 | 380..453 | CDD:400301 | 31/89 (35%) | ||
KCNK1 | NP_002236.1 | Ion_trans_2 | <101..157 | CDD:400301 | 18/55 (33%) |
pore-forming domain | 107..123 | 6/15 (40%) | |||
Ion_trans_2 | 192..267 | CDD:400301 | 27/74 (36%) | ||
pore-forming domain | 212..238 | 14/25 (56%) | |||
Important for intracellular retention in recycling endosomes. /evidence=ECO:0000269|PubMed:19959478 | 293..299 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C165155158 | |
Domainoid | 1 | 1.000 | 57 | 1.000 | Domainoid score | I10857 |
eggNOG | 1 | 0.900 | - | - | E1_KOG1418 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.740 |