Protein Alignment CG42340 and twk-43

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_872137.2
• Gene: twk-43 / 3565024
• WormBaseID: WBGene00006693
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 103/563 - (18%)
• Similarity: 206/563 - (36%)
• Gaps: 146/563 - (25%)

  Fly    90 KSHCISATGVLLLVLLYTAMGSIVFVTLEG---ELEDGGAL-----------------ETAVAAS 134
            |.:.::| |::|.|.:|...|:::...:|.   ::|:...|                 |..:.|.
 Worm    36 KPYLLNA-GIVLFVGIYVYAGALLIQYIERIPVKVEESFRLRRNSQDDMPIIPLDRSKECVLQAL 99

  Fly   135 KPYPRTELANAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDT--------LLRAVRQ 191
            :...:....|..          .:..::|:|  ||......|:::...|:        ...||..
 Worm   100 RKMSQISKGNCS----------QLHNNVNLL--ENCYASDLQKLKTIYDSSEGSKAPEQQSAVAL 152

  Fly   192 SKVYPPGGIQLNAPTHKWTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYL 256
            .|.....|.:      :||...|.|:..|:|||||||.::|::.||||..::|...|||..::.:
 Worm   153 KKFVIVDGFE------QWTTTDAILFCFTVITTIGYGNVAPQSFWGRVFVIIYGTIGIPTAMMAI 211

  Fly   257 SAMGEALSAGMR---------CLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQG 312
            :.:|:.|:..::         |...::|:                          :|.|:| |..
 Worm   212 ANVGKFLATLLKSWTRPFLLLCRKMKKRM--------------------------QKKDQN-GNE 249

  Fly   313 HYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISIC 377
            ....|:|          .:...::|::.:...:....:..:::|::          |......:.
 Worm   250 IKETQRL----------MESSKKKAKKIEDDISSHEDEEAEEEVEE----------SDVTETIVL 294

  Fly   378 VCVLLCYVSSGAILFHKLQNWSVLE-SLYFCFTSLGTIGFGEMAPNGAVALYTASAYILVGMAVV 441
            ....|.|:.:|::|....:...... ::||.|.:|.|||.|::.|.....|:....|..:|:|:.
 Worm   295 FVAFLVYIIAGSLLMSYYEEGMTFGLAIYFNFVTLTTIGLGDLVPQSTDWLFVTLVYCAIGLALT 359

  Fly   442 AMCFSL-----------------IQTEIVLWL--RRFSVQDHVMPKAEELALVTVAVTPKPSXQR 487
            .:...:                 :| .:.:|.  ::.|::..|....::|.:        |..:.
 Worm   360 TIAIEIAADTLKKLHYFGRKLDNVQ-NVQIWFGGQKLSMKALVKNLGDQLNV--------PVEEL 415

  Fly   488 PSADPSLGVGLGVGLAGGALGQPQN-----NLGQHQTMFFGPAHTLTQYSSLPRRSHLQAANNSG 547
            .:.|.:..|...:.:..|.|...:|     |....:.:..|..|.:.....:..:|:|     |.
 Worm   416 ENLDLAKFVDDAIKVEAGELTTLRNDRAWMNSNYWRAIESGSMHYVDDDDLVTLQSNL-----SC 475

  Fly   548 GGSAFQRNTPIRRSTG---IPEHHLEYFVPRSISEFNLSGVGD 587
            |........|..|||.   |..:| |.....|...|.|..|.:
 Worm   476 GSQQMLIRVPYSRSTDSRMITVNH-EPLTETSDENFKLHSVNE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	22/55 (40%)
		Ion_trans_2	380..453	CDD:400301	18/90 (20%)
twk-43	NP_872137.2	Ion_trans_2	<162..218	CDD:285168	22/61 (36%)
		Ion_trans_2	298..372	CDD:285168	17/73 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010