Protein Alignment CG42340 and twk-43

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_872137.2
• Gene: twk-43 / 3565024
• WormBaseID: WBGene00006693
• Length: 597
• Species: Caenorhabditis elegans
• Alignment Length: 563
• Identity: 103/563 - (18%)
• Similarity: 206/563 - (36%)
• Gaps: 146/563 - (25%)

  Fly    90 KSHCISATGVLLLVLLYTAMGSIVFVTLEG---ELEDGGAL-----------------ETAVAAS 134
            |.:.::| |::|.|.:|...|:::...:|.   ::|:...|                 |..:.|.
 Worm    36 KPYLLNA-GIVLFVGIYVYAGALLIQYIERIPVKVEESFRLRRNSQDDMPIIPLDRSKECVLQAL 99

  Fly   135 KPYPRTELANAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDT--------LLRAVRQ 191
            :...:....|..          .:..::|:|  ||......|:::...|:        ...||..
 Worm   100 RKMSQISKGNCS----------QLHNNVNLL--ENCYASDLQKLKTIYDSSEGSKAPEQQSAVAL 152

  Fly   192 SKVYPPGGIQLNAPTHKWTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYL 256
            .|.....|.:      :||...|.|:..|:|||||||.::|::.||||..::|...|||..::.:
 Worm   153 KKFVIVDGFE------QWTTTDAILFCFTVITTIGYGNVAPQSFWGRVFVIIYGTIGIPTAMMAI 211

  Fly   257 SAMGEALSAGMR---------CLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQG 312
            :.:|:.|:..::         |...::|:                          :|.|:| |..
 Worm   212 ANVGKFLATLLKSWTRPFLLLCRKMKKRM--------------------------QKKDQN-GNE 249

  Fly   313 HYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISIC 377
            ....|:|          .:...::|::.:...:....:..:::|::          |......:.
 Worm   250 IKETQRL----------MESSKKKAKKIEDDISSHEDEEAEEEVEE----------SDVTETIVL 294

  Fly   378 VCVLLCYVSSGAILFHKLQNWSVLE-SLYFCFTSLGTIGFGEMAPNGAVALYTASAYILVGMAVV 441
            ....|.|:.:|::|....:...... ::||.|.:|.|||.|::.|.....|:....|..:|:|:.
 Worm   295 FVAFLVYIIAGSLLMSYYEEGMTFGLAIYFNFVTLTTIGLGDLVPQSTDWLFVTLVYCAIGLALT 359

  Fly   442 AMCFSL-----------------IQTEIVLWL--RRFSVQDHVMPKAEELALVTVAVTPKPSXQR 487
            .:...:                 :| .:.:|.  ::.|::..|....::|.:        |..:.
 Worm   360 TIAIEIAADTLKKLHYFGRKLDNVQ-NVQIWFGGQKLSMKALVKNLGDQLNV--------PVEEL 415

  Fly   488 PSADPSLGVGLGVGLAGGALGQPQN-----NLGQHQTMFFGPAHTLTQYSSLPRRSHLQAANNSG 547
            .:.|.:..|...:.:..|.|...:|     |....:.:..|..|.:.....:..:|:|     |.
 Worm   416 ENLDLAKFVDDAIKVEAGELTTLRNDRAWMNSNYWRAIESGSMHYVDDDDLVTLQSNL-----SC 475

  Fly   548 GGSAFQRNTPIRRSTG---IPEHHLEYFVPRSISEFNLSGVGD 587
            |........|..|||.   |..:| |.....|...|.|..|.:
 Worm   476 GSQQMLIRVPYSRSTDSRMITVNH-EPLTETSDENFKLHSVNE 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	22/55 (40%)
		Ion_trans_2	380..453	CDD:462301	18/90 (20%)
twk-43	NP_872137.2	Ion_trans_2	155..218	CDD:462301	23/68 (34%)
		Ion_trans_2	298..372	CDD:462301	17/73 (23%)