Protein Alignment CG42340 and twk-10

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_001300134.1
• Gene: twk-10 / 192080
• WormBaseID: WBGene00006665
• Length: 429
• Species: Caenorhabditis elegans
• Alignment Length: 515
• Identity: 100/515 - (19%)
• Similarity: 181/515 - (35%)
• Gaps: 172/515 - (33%)

  Fly    98 GVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYP-----------RTELANAEIRSRT 151
            |::||.:||...|::.|:..|...|.    .......|.|.           |.:|.:.....|.
 Worm    41 GLILLCILYVHFGALFFMYSESPEEQ----RILRRVEKRYDILRETFLENVNRVKLEDFSDERRV 101

  Fly   152 VDRLWSITEDLNILYKENWTRLAAQEV--QLFQDTLLRAVRQSKVYPPGGIQLNAPTHKWTYASA 214
            .:.:..:.:|    |.::..:|....|  .:| |.|..:  ||...|           .||..|:
 Worm   102 NESISRLIDD----YSKHMFKLFTNPVAANMF-DCLFYS--QSNYTP-----------LWTTDSS 148

  Fly   215 FLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGG 279
            .|::.|.|..:|||.|:|.|..||:...:||.||||:.|:.:|.:|:        .|....||
 Worm   149 LLFTATTIIPVGYGYIAPLTSTGRIVLCIYAAFGIPLALVMMSDVGK--------FFADAFVK-- 203

  Fly   280 PGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQ 344
                                              :.|:.:..:
 Worm   204 ----------------------------------FFHENITAF---------------------- 212

  Fly   345 AQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVLESLYFCFT 409
                                         :.:.:.:|:.|...|.|.:.|:....::|.:||...
 Worm   213 -----------------------------MVVLLILLVAYSVIGGIAYSKIVGVPMIEGVYFSTI 248

  Fly   410 SLGTIGFGEMAPNGAVALYTASAYILVGMAVVAMCFSLIQTEIVLWLRRFSVQDHVMPKAEELAL 474
            ::.|||||::.|  .:.:|....:|:.|:|:|.:...::...|:..:.....|   :.:|:.:|.
 Worm   249 TIFTIGFGDITP--GIPVYVIIIFIVFGVAIVTIAIDVVAANIIHHIHYMGRQ---VGRAKIIAD 308

  Fly   475 VTVAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQPQNNLGQHQTMFFGPAHTLTQYSSL-PRRS 538
            ..:::..|.|..|         |||:|:|         .||.     |.....:...|:: |:..
 Worm   309 KMLSMAQKISINR---------GLGLGMA---------QLGA-----FARMGMMINVSAMGPQDG 350

  Fly   539 HLQAANNSGGGSAFQRNT--------PIRRSTGI-PE---HHLEYFVPRSISEFNLSGVG 586
            |.......||....:::|        ..|:||.. |:   ..:::..|...|:: |.|.|
 Worm   351 HANGGVGEGGIEMSRKSTWRSENDEIKTRKSTAFEPDLDFDMIDFRQPSGSSQY-LYGFG 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	23/55 (42%)
		Ion_trans_2	380..453	CDD:462301	19/72 (26%)
twk-10	NP_001300134.1	Ion_trans_2	128..199	CDD:462301	30/92 (33%)
		Ion_trans_2	218..286	CDD:462301	19/69 (28%)