Protein Alignment CG42340 and twk-21

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_510654.2
• Gene: twk-21 / 192078
• WormBaseID: WBGene00006674
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 78/388 - (20%)
• Similarity: 139/388 - (35%)
• Gaps: 140/388 - (36%)

  Fly    99 VLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDRLWSITEDLN 163
            ::|::|.|..:|..:|..||                  |.:.:|.
 Worm   137 LILIILGYACLGGYMFQALE------------------YDQQQLE-------------------- 163

  Fly   164 ILYKENWTRLAAQEVQLFQDTLLRAVRQ---------------SKVYPPGGIQLNAPTHKWTYAS 213
             |..|...||:  |..|....||..::|               :|.:.....:......:|.:.:
 Worm   164 -LEAEKRVRLS--ESSLLAVNLLEHLKQMNCGQSNEKRCLELITKTFIQRSDEERGEGWRWDFWN 225

  Fly   214 AFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKG 278
            :..:|.|:.||||||.::.:|..||:|.::|.:.|||::|..|...||.      |:...:::
 Worm   226 SVFFSATIFTTIGYGNLACKTNLGRIATIIYGMIGIPLMLFVLKNFGEL------CVKWAKKI-- 282

  Fly   279 GPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQ 343
                                                      |:.:      ||..::....:|:
 Worm   283 ------------------------------------------QFNV------QQCLKKCFGRKQK 299

  Fly   344 QAQQAQQAQQQ-------QVQQGKKSSGN---RRGSPSVPISICVCVLLCYVSSGAILFHKLQNW 398
            :|........:       :|.:..|....   |.|       :.|.||...:.|..:.|  .:||
 Worm   300 RASSLASITSKEMLEVFFEVPEDDKEDTTFQLRWG-------LLVIVLFVVLCSFVVSF--WENW 355

  Fly   399 SVLESLYFCFTSLGTIGFGEMAPN---GAVALYTASAYILVGMAVVAMCFSLIQTEI---VLW 455
            ..|.:.||.|.||.|||||::.|:   .|.||:   ....:|:|:.||.::::|..:   .:|
 Worm   356 DFLTAFYFFFVSLSTIGFGDIVPDHPRTACALF---VLYFIGLALFAMVYAILQERVENQYMW 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	21/55 (38%)
		Ion_trans_2	380..453	CDD:400301	26/78 (33%)
twk-21	NP_510654.2	Ion_trans_2	<219..277	CDD:285168	22/63 (35%)
		Ion_trans_2	345..411	CDD:285168	24/70 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163790
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750