Protein Alignment CG42340 and twk-25

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_502170.4
• Gene: twk-25 / 192076
• WormBaseID: WBGene00006678
• Length: 683
• Species: Caenorhabditis elegans
• Alignment Length: 557
• Identity: 106/557 - (19%)
• Similarity: 166/557 - (29%)
• Gaps: 230/557 - (41%)

  Fly    99 VLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDR-LWSI--TE 160
            :||||||||.:|:.:|.::|.                   |.|........|.:|| ::.|  |.
 Worm   292 MLLLVLLYTLLGAALFFSIES-------------------RHEHETMHFHKRKLDRIIYEIAQTL 337

  Fly   161 DLNILYKENWTRLAAQE-------VQLFQ-DTLLRAVRQSKVYPPGGIQLNAPTHKWTYASAFLY 217
            :|.:|.....|.:...|       |:|.. :.|.......|...|..:       ||||.|||.:
 Worm   338 ELEVLDPMKLTNITQMEYFITRAYVKLLNAEDLYSGSTFYKHEDPKNL-------KWTYGSAFFF 395

  Fly   218 SLTLITTIGYGGISPRTQWGRVAALVYALFGIPI-----------VLLYLSAMGEALSAGMRCLF 271
            |:.:.||.|||.|:|.:..|:...:||.|..:|:           .||||:.|...|...    |
 Worm   396 SMNVYTTTGYGSIAPSSSLGKALVIVYGLIFVPLTAVVIRDLGQWALLYLTKMYTILIDS----F 456

  Fly   272 RRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQ 336
            ||.|                        |...|.|:::
 Worm   457 RRVR------------------------GFVDKLDEDE--------------------------- 470

  Fly   337 AQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNW--- 398
                                            ..::||...|.|::.|:.|..:...:....
 Worm   471 --------------------------------IITLPIKFSVSVMILYLLSATMFIFEYDELSGP 503

  Fly   399 -----SVLESLYFCFTSLGTIGFGEMAPNGAVALYTASAYILVGMAVVAMCFSLIQTEIVLWLRR 458
                 |...:.||.|.|:.|||.|::.||........:.....||.::         ::|..:..
 Worm   504 PDSGISFFHAFYFSFISMSTIGLGDVMPNNVTFSPLITIMFFFGMPIL---------KVVNRVTY 559

  Fly   459 FSVQDHVMPK----AEELALVTVAVTPKPSXQRPSADPSLGVG------LGVGLAGGALGQPQNN 513
            ..:::.|...    ...|..:....|..|:.|..|..|::.|.      |..|:.      |..|
 Worm   560 ICLENGVFGSMTVLENRLDTIWSKATVLPTGQVISEPPTIDVASRKTSMLSEGMI------PDEN 618

  Fly   514 LGQHQTMFFGPAHTLTQYSSLPRRSHLQAANNSGGGSAFQRNTPIRRSTGIPEHHLEYFVPRSIS 578
            .|                                               .:|..:|..|..|||:
 Worm   619 DG-----------------------------------------------SVPNEYLNNFTIRSIA 636

  Fly   579 EFNLSGVGDLALPPPRRYSPNMVGGGGGMGGMGMNMG 615
            .| :...||:.              ||..|.:.:..|
 Worm   637 TF-MKANGDVY--------------GGAFGRVNIRRG 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	25/66 (38%)
		Ion_trans_2	380..453	CDD:400301	16/80 (20%)
twk-25	NP_502170.4	Ion_trans_2	370..440	CDD:285168	23/76 (30%)
		Ion_trans	<482..555	CDD:278921	16/81 (20%)
		Ion_trans_2	482..551	CDD:285168	16/68 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010