Protein Alignment CG42340 and twk-1

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_001293466.1
• Gene: twk-1 / 192072
• WormBaseID: WBGene00006656
• Length: 451
• Species: Caenorhabditis elegans
• Alignment Length: 349
• Identity: 62/349 - (17%)
• Similarity: 127/349 - (36%)
• Gaps: 107/349 - (30%)

  Fly   120 ELEDGGALETAVAASKPYPRTELANAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDT 184
            |.|..|.:|..:.:.|  .:.:|.:      .:||.:.:..|.....|....::..:|: :|..|
 Worm    14 EEEHAGLIENQIISQK--TKKQLPS------WLDRPYHVWRDQFQQDKCCPKKMVKREL-MFAST 69

  Fly   185 LLRAVRQSKV-YPPGGIQL-----NAPTHKWTYASAFLYSLTLITTIGYGGISPRTQWGRVAALV 243
            .:..:..:.: |...|.|:     ::..::.::....|:.:|.|:|||||.|:|....|:|..::
 Worm    70 YVLILNVALILYVLFGCQVFDLRHSSTNNEASFLDRALFCITTISTIGYGNIAPFDDRGKVICIL 134

  Fly   244 YALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKN 308
            |.:.|||:..:.: |....|...:..:..|.
 Worm   135 YCVAGIPLFFMTV-ATNSVLVVDICNIVHRS---------------------------------- 164

  Fly   309 KGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVP 373
                                |..|..:                          :||.|..:.::
 Worm   165 --------------------YSSQNVE--------------------------NSGFRWYTSAI- 182

  Fly   374 ISICVCVLLCYVSSGAILFHK-LQNWSVLESLYFCFTSLGTIGFGEMA--PNGAVALYTASAYIL 435
                :....|::  ||::|.. :.....|::.||.|.|:.|||:|:.:  |.|.......:.|:.
 Worm   183 ----LLAAHCFI--GALIFSLWIDQLDFLDAFYFSFISITTIGYGDYSPTPEGLFQYIIVTVYLC 241

  Fly   436 VGMAVVAMCFSLIQTEIVLWLRRF 459
            .|:|.:.:.|:.:|..| :|:..:
 Worm   242 TGVATMLLFFASLQKGI-MWIHYY 264

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	17/55 (31%)
		Ion_trans_2	380..453	CDD:462301	20/75 (27%)
twk-1	NP_001293466.1	Ion_trans_2	76..149	CDD:462301	19/73 (26%)
		Ion_trans_2	182..256	CDD:462301	19/80 (24%)