Protein Alignment CG42340 and twk-45

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_001122742.2
• Gene: twk-45 / 190614
• WormBaseID: WBGene00006695
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 555
• Identity: 118/555 - (21%)
• Similarity: 195/555 - (35%)
• Gaps: 183/555 - (32%)

  Fly    92 HCISATGVLLLVLL--YTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDR 154
            |......:.|:.:|  |..:|..:|..||...|.....||          .:..|..|::.|:|
 Worm    80 HKFGIRHITLISILAAYICLGGFLFQKLESPREIEELQET----------LKSMNEIIKNETMD- 133

  Fly   155 LWSIT-----EDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHK------ 208
            :..||     ||.|               |...| ||||..:..:...|....:| .||
 Worm   134 IIKITLTTNGEDRN---------------QKLGD-LLRAYHRILLETEGKFHGSA-WHKSENLDM 181

  Fly   209 ---WTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCL 270
               |.::||..||:||.:|||||.|:.:|.||:..::|||..|:||:||.|..:|
 Worm   182 NLMWYFSSATFYSMTLFSTIGYGTITCQTFWGKTVSMVYASIGLPIMLLVLGDIG---------- 236

  Fly   271 FRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQ 335
                                                                     |:.|:...
 Worm   237 ---------------------------------------------------------VWFQKVMT 244

  Fly   336 QAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYV---SSGAILFHKLQ- 396
            .|......:.:..:          |:|...:|....:|:.:.:.|:..|:   :...:||...:
 Worm   245 NAYIFVMLKYKSLR----------KQSIEIKRKETLLPMWLAMLVVFTYIIICTLTILLFDDNEG 299

  Fly   397 ---NWSVLESLYFCFTSLGTIGFGEMAP-NGAVALYTASAYILVGMAVVAMCFSLIQTEIVLWLR 457
               ..:..::.||.|.||.|||.|::.| |...:.:...|::| |:|::    |::.|.|...|.
 Worm   300 DEPGINFFDAFYFTFISLTTIGLGDVMPYNIQYSPFLPLAFLL-GLALI----SIVNTSIYSTLY 359

  Fly   458 R------FSVQDHVMPKAEELALVTVAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQPQNNLGQ 516
            :      :|::|.:                    .|.......|       ||..:.|...:..|
 Worm   360 QSFYNLIYSLEDQL--------------------DRIHNSRRRG-------AGYRVFQDMESTFQ 397

  Fly   517 HQTMFF--GPAHTLTQYSSLPRRSHLQAANNSGGGSAFQRNTPIRRSTGIPEHHLEYFVPRSISE 579
            .....|  .|||:..:::||.|.|..:|...|.     |.....|..:.||:...::...||
 Worm   398 MLVCTFPPSPAHSRIRFASLIRDSFREAKKESA-----QPKVRTRTESDIPDGFQQWMAKRS--- 454

  Fly   580 FNLSGVGDLALPPPRRYSPNMVGGGGGMGGMGMNM 614
            ..|....|..  ..:|.:|.:    |.:||..|::
 Worm   455 RRLHSADDEM--KEKRRAPTL----GALGGFDMSL 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	27/64 (42%)
		Ion_trans_2	380..453	CDD:400301	21/80 (26%)
twk-45	NP_001122742.2	Ion_trans_2	<185..241	CDD:285168	27/122 (22%)
		Ion_trans_2	278..354	CDD:285168	21/80 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163744
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D542195at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950