Protein Alignment CG42340 and twk-20

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_510284.1
• Gene: twk-20 / 181485
• WormBaseID: WBGene00006673
• Length: 364
• Species: Caenorhabditis elegans
• Alignment Length: 516
• Identity: 105/516 - (20%)
• Similarity: 187/516 - (36%)
• Gaps: 189/516 - (36%)

  Fly    95 SATGVLLLVLLYTAM--GSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDRLWS 157
            ||..:||::..:|.:  |::||..||.|.:             .:.|.|:      .|..|||
 Worm     8 SARALLLILSTFTYLLFGAMVFDKLESEKD-------------TWVRDEI------ERITDRL-- 51

  Fly   158 ITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHKWTYASAFLYSLTLI 222
                   .:|.|::.   :::.||:...::::.|...|            :|.:|.||.::..:|
 Worm    52 -------KHKYNFSE---RDLHLFEAIAIKSIPQQAGY------------QWQFAGAFYFATVVI 94

  Fly   223 TTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGG 287
            ||:|||..:|.|..|::..:::||||:|:.|:...::||.::..:.....:.|
 Worm    95 TTVGYGHSAPSTNAGKLFCMIFALFGVPMGLIMFQSIGERVNTFIAYSLHKFR------------ 147

  Fly   288 ASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQ 352
                                         ..|||.|.                          ..
 Worm   148 -----------------------------DSLHQQGF--------------------------TC 157

  Fly   353 QQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVLESLYFCFTSLGTIGFG 417
            .|:|            :|:..:.:.:.:....:.||..:||.::.||:.::.|||..:..|||||
 Worm   158 LQEV------------TPTHLLMVSLTIGFMVIVSGTYMFHTIEKWSIFDAYYFCMITFSTIGFG 210

  Fly   418 EMAP--------NGAVALYTASAYILVGMAVVAMCFSLIQTEIVLWLRRFSVQDHVMPKAEELAL 474
            ::.|        :..:.::....:||:|:||.:.|.:|:            |...:...|:|
 Worm   211 DLVPLQQVNALQDQPLYVFATIMFILIGLAVFSACVNLL------------VLGFMASNADE--- 260

  Fly   475 VTVAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQPQNNLGQHQTMFFGPAHTLTQYSSLPRRS- 538
            ||.|       ||   :|...:.|........:.....|:.:|.|:...|......||.:|..:
 Worm   261 VTAA-------QR---EPPSAIVLERFTRNSLVDSQIFNIQKHSTVGVLPGRPRRMYSIVPNSTA 315

  Fly   539 --HLQAANNSGGGSAFQRNTPIRRSTGIPEHHLEYFVPRSISEFNLSGVGDLALPPPRRYS 597
              ||:                 ||||           .|||.:....|... ..||..|:|
 Worm   316 DVHLR-----------------RRST-----------RRSIQDTVCCGCFK-PRPPRHRFS 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	21/55 (38%)
		Ion_trans_2	380..453	CDD:462301	22/80 (28%)
twk-20	NP_510284.1	Ion_trans_2	<78..135	CDD:462301	22/68 (32%)
		Ion_trans_2	175..250	CDD:462301	22/86 (26%)