Protein Alignment CG42340 and twk-26

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_508522.2
• Gene: twk-26 / 180592
• WormBaseID: WBGene00006679
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 120/565 - (21%)
• Similarity: 196/565 - (34%)
• Gaps: 192/565 - (33%)

  Fly    92 HCISATGVLLLVLL--YTAMGSIVFVTLEG--ELEDGGALETAVAASK--PYPRTELANAEIRSR 150
            |......|.|:.||  |..:|..:|..||.  ||||  ..||.|....  ....|::.|..:.:.
 Worm    80 HKFGIRHVTLIALLVGYVFLGGFMFEKLESPRELED--LKETIVLMQGIIDEETTDIINVTLSTN 142

  Fly   151 TVDRLWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTH-KWTYASA 214
            ..||:..:.:.:...||   |.|.|:  ..|..::.....            |...| .|.::||
 Worm   143 GTDRVNKLAKLIKRYYK---TMLEAE--GRFHGSVWHKAE------------NLDMHLMWYFSSA 190

  Fly   215 FLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGE----ALSAGMRCLFRRQR 275
            ..||:||.:|||||.||.:|.|||..:::||..|:||:|:.|..:||    .|:.|...|..:
 Worm   191 TFYSMTLFSTIGYGTISCQTVWGRTLSMIYASIGLPIMLVVLGDIGEWFQKILTNGYIFLLLK-- 253

  Fly   276 VKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQA 340
                                                    ::||.
 Worm   254 ----------------------------------------YKKLR-------------------- 258

  Fly   341 QQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILF----HKLQN---W 398
                               |:....::....:|:.:.:.::|.|:....:..    |...|   .
 Worm   259 -------------------KQPVNRKKNEILLPMWLALFLVLAYILICTLTIKMFDHNEGNKPGI 304

  Fly   399 SVLESLYFCFTSLGTIGFGEMAP-NGAVALYTASAYILVGMAVVAMCFSLIQTEIVLWLRRF--- 459
            ...::.||.|.||.|||.|::.| |...:.:.|:|::| |:|::    |::.|.|...|.:.
 Worm   305 GFFDAFYFTFISLTTIGLGDVMPYNIQYSPFLAAAFLL-GLALI----SIVNTSIYAQLYQMFFN 364

  Fly   460 ---SVQDHVMPKAEELALVTVAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQPQNNLGQHQTMF 521
               ||:|.:                    .|..:....|.|..|             ....:.:|
 Worm   365 MINSVEDQL--------------------DRIHSSNHKGPGYKV-------------FHDMEPVF 396

  Fly   522 ------FGPAH--TLTQYSSLPR---RSHLQAANNSGGGSAFQRNTPIRRSTGIPEH---HL--- 569
                  |.|:|  |..:::::.|   |...:....|......:..|  |..:.||.|   ||
 Worm   397 RMLVCTFPPSHPQTRIKFAAVVRDSFRRDKEKKRESNTSDQIKLRT--RTESDIPAHDGFHLWMT 459

  Fly   570 EYFVPRSISEFNLSGVGDLALPPPRRYSPNMVGGGGGMGGMGMNM 614
            :....|.:.:.|..      |...||.:|.:    |..||..||:
 Worm   460 KRAKKRQMEQENED------LHAARRRAPTL----GAFGGFDMNL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	27/59 (46%)
		Ion_trans_2	380..453	CDD:462301	22/80 (28%)
twk-26	NP_508522.2	Ion_trans_2	<184..241	CDD:462301	27/56 (48%)
		Ion_trans_2	278..>327	CDD:462301	13/48 (27%)