Protein Alignment CG42340 and twk-34

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_506906.3
• Gene: twk-34 / 180054
• WormBaseID: WBGene00006686
• Length: 558
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 107/584 - (18%)
• Similarity: 177/584 - (30%)
• Gaps: 248/584 - (42%)

  Fly    99 VLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDRLWSITEDLN 163
            |.|:||.||..|:.:|.|:|...|                         |:.|::|:.::...||
 Worm   169 VALMVLSYTIFGAFMFWTVESRNE-------------------------RAVTLERVTNLENLLN 208

  Fly   164 IL--------YKENWTRLAAQEVQLF----QDTLLRAVRQSKVYPPGGIQLNAPTH----KWTYA 212
            ||        ...|.|...| |:|::    ..:|::...|.|    |........|    |||:.
 Worm   209 ILATNITEIVNNPNTTTTEA-EMQVYIREAYVSLMKLEGQYK----GSTYYKLEDHGKNWKWTFE 268

  Fly   213 SAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVK 277
            |||.:|:.:.||.|||.|:|.:..|:|...:|....:|:.|:.|..:|:.....:..|:
 Worm   269 SAFFFSMNVYTTTGYGSIAPESILGQVLVCLYGFIFVPVTLVALRDLGQFFLVHLTKLY------ 327

  Fly   278 GGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQ 342
                                                                             
 Worm   328 ----------------------------------------------------------------- 327

  Fly   343 QQAQQAQQAQQQQVQQGKKSSGNRRGSPS----VPISICVCVLLCYVSSGAILFHKLQNWSVLES 403
                      .|.:|:.::.:|:.....:    :||..|:.:|..|::...|..|.....|..||
 Worm   328 ----------AQLIQRWREINGDTSIDVNEIIKIPIKACLLLLALYLAFCTIFIHVFDELSGDES 382

  Fly   404 ---------LYFCFTSLGTIGFGEMAPNGAVALYTASAYILVGMAVVAM---------------C 444
                     .||.|.||.|||.|::.||.|......|.....|||:..:               .
 Worm   383 GSGMSVFLCFYFSFISLSTIGLGDIMPNNATFSPIISIMFFFGMALTKVVNRNTFIAVENGIFGA 447

  Fly   445 FSLIQTEIVLWLRRFSVQDHVMPKAEELALVTVAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQ 509
            .:|::.::          |.::.|.:|:        |....|..:..|.:
 Worm   448 LTLVENKL----------DGIVRKGKEM--------PDEQKQPKALTPQM--------------- 479

  Fly   510 PQNNLGQHQTMFFGPAHTLTQYSSLPRRSHLQAANNSGGGSAFQRNTPIRRSTGIPEHHLEYFVP 574
                        ...|.::..|.:..|.:..:..||                          |..
 Worm   480 ------------IQRALSVEDYGAAQRENKNEVMNN--------------------------FTV 506

  Fly   575 RSISEFNLSGVGDLALPPPRRYSPNMVGGGGGMGGMGMNMGGMGMNMGMGMGLPHGLQLGPPQT 638
            |||:.|..|.. |:.              |||.|.:.:..|.:       ||..|.:.....:|
 Worm   507 RSIATFMKSNT-DIY--------------GGGFGRVQLRRGDL-------MGSDHQMTTSSEKT 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	21/55 (38%)
		Ion_trans_2	380..453	CDD:400301	24/96 (25%)
twk-34	NP_506906.3	Ion_trans_2	250..319	CDD:285168	23/68 (34%)
		Ion_trans_2	366..442	CDD:285168	21/75 (28%)
		Ion_trans	<387..449	CDD:278921	16/61 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163785
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840