Protein Alignment CG42340 and egl-23

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_001255775.1
• Gene: egl-23 / 178358
• WormBaseID: WBGene00001190
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 112/613 - (18%)
• Similarity: 192/613 - (31%)
• Gaps: 238/613 - (38%)

  Fly   199 GIQLNAPTHKWTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEAL 263
            |.:......:|::..:.|::.|:|||||||.::|||..||:..:.|.|.|||..||.::.:|:.:
 Worm   210 GEEAEEDVSEWSFMDSLLFAFTVITTIGYGNVAPRTFGGRLFVIGYGLIGIPFTLLAIADLGKFI 274

  Fly   264 SAGMRCLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSV 328
            |..|                            .......|||.|          ||.:...|..:
 Worm   275 SEMM----------------------------VEAKSFCRKTWK----------KLKKAWNPNFI 301

  Fly   329 YQQQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFH 393
                :|:.......::.....:..:.:.:..:.|......:.:...|:.: :.|.|::.|..:..
 Worm   302 ----RAKDLSNTDIEEKILDNEKIENEPETSEVSEEEDDLTETEATSLFI-LFLVYIAFGGFMLA 361

  Fly   394 KLQ-NWSVLESLYFCFTSLGTIGFGEMAPNGAVALYTASAYILVGMAVVAMCFSLIQT------- 450
            ..: :....:::||.|.:|.:||.|::.|.....:.....||.:|:|:..:...:...
 Worm   362 AYEPDMDFFKAVYFNFVTLTSIGLGDIVPRSETYMLITIVYIAIGLALTTIAIEIAADALKKLHY 426

  Fly   451 ---------EIVLWL--RRFSVQ----------------------DHVMP---KAEELALVTVAV 479
                     .:.:|.  ::.:::                      ||.:.   |.||..:.|:..
 Worm   427 FGRKIENVGNVAIWFGGKKITMKALVKNLGDQFNLPTTVVKNLNLDHFVDQAIKVEEGEIETLRP 491

  Fly   480 TP-KPSXQR------------------PSADPSLGVGLGVGLAGGALGQPQNNLGQHQ--TMFFG 523
            .| :|...|                  |:..||              .||...|...:  |....
 Worm   492 PPYEPPSDRFEAEFADEPECEWIRDPTPTPPPS--------------PQPVYRLPSPKPVTPEPL 542

  Fly   524 PAHTLTQYSSLPRRSHLQAANNSGGGSAFQRN--------TPIRRSTGIPEHHLEYFVPRSISEF 580
            |:.|:|..|       |..|..|...|...:.        :|:|..|..|.       ||.
 Worm   543 PSPTITDVS-------LAIATPSPEESDDDQELILPSPEPSPVREPTPPPP-------PRE---- 589

  Fly   581 NLSGVGDLALPPPRRYSPNMVGGGGGMGGMGMNMGGMGMNMGMGMGLPHGLQLGPPQTLLCSAAP 645
                      |.||..:|.                                    |:
 Worm   590 ----------PTPREPTPE------------------------------------PE-------- 600

  Fly   646 TVQQQQQPPPPPAQLQIVTLKPR--------SEKMVTFEDES--------KQ-----------AV 683
            .|::...||||||       |||        ::|...:.:|:        ||           |.
 Worm   601 PVREPTPPPPPPA-------KPRPLTAAEIAAQKRKAYSEEAWRRYQEYQKQWKKFRQTQKTPAP 658

  Fly   684 GGGAVGGVAGG--SGTPPHCPHGVPTTP 709
            .|.:..|.:..  |||.|....||.|.|
 Worm   659 SGASTSGASTSKPSGTSPESGAGVCTGP 686

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	23/55 (42%)
		Ion_trans_2	380..453	CDD:400301	15/89 (17%)
egl-23	NP_001255775.1	Ion_trans_2	216..276	CDD:285168	23/59 (39%)
		Ion_trans_2	347..423	CDD:285168	15/76 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163797
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940