Protein Alignment CG42340 and twk-3

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_495727.1
• Gene: twk-3 / 174321
• WormBaseID: WBGene00006658
• Length: 383
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 97/467 - (20%)
• Similarity: 167/467 - (35%)
• Gaps: 147/467 - (31%)

  Fly    97 TGVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDRLWSITED 161
            ||::|..:.|...|:.:|:::|...|              ..|.|.|..|.:......:.:||..
 Worm    42 TGLVLSCVTYALGGAYLFLSIEHPEE--------------LKRREKAIREFQDLKQQFMGNITSG 92

  Fly   162 LNILYKENWTRLAAQEVQLFQDTL---LRAVRQSKVYPPGGIQLNAPTHKWTYASAFLYSLTLIT 223
            :     ||    :.|.::::...|   |.....:..:....:....|...||::||.:::.|.:.
 Worm    93 I-----EN----SEQSIEIYTKKLILMLEDAHNAHAFEYFFLNHEIPKDMWTFSSALVFTTTTVI 148

  Fly   224 TIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGGA 288
            .:|||.|.|.:.:||:..:.|||.|||:.|:.::..|:         |..|.|....|
 Worm   149 PVGYGYIFPVSAYGRMCLIAYALLGIPLTLVTMADTGK---------FAAQLVTRWFG------- 197

  Fly   289 SGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQ 353
                             |.|.
 Worm   198 -----------------DNNM-------------------------------------------- 201

  Fly   354 QQVQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVLESLYFCFTSLGTIGFGE 418
                             ::|.:|.||:|..|......:.....|.:.|:|:||..||:.|||||:
 Worm   202 -----------------AIPAAIFVCLLFAYPLVVGFILCSTSNITYLDSVYFSLTSIFTIGFGD 249

  Fly   419 MAPNGAVALYTASAYILVGMAVVAMCFSLIQTEIVLWLRRFSVQDHVMPKAEELALVTVAVTPKP 483
            :.|:  :.:.....::.||:.:|.:...::..|::   .|.......:.||:|||       .|.
 Worm   250 LTPD--MNVIHMVLFLAVGVILVTITLDIVAAEMI---DRVHYMGRHVGKAKELA-------GKM 302

  Fly   484 SXQRPSADPSLGVGLGVG----LA--GGALGQPQNNLGQHQTMF-FGP--------AHTLTQYSS 533
            .....|.:...|:..|||    ||  |..:|:.:.:..|...:. |.|        ..||:.||.
 Worm   303 FQLAQSLNMKQGLVSGVGQLHALARFGMLVGREEVDKTQEDGIIAFSPDVMDGLEFMDTLSIYSR 367

  Fly   534 LPRRSHLQAANN 545
            ..|||...:|.|
 Worm   368 RSRRSAENSARN 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	20/55 (36%)
		Ion_trans_2	380..453	CDD:462301	19/72 (26%)
twk-3	NP_495727.1	Ion_trans_2	<133..190	CDD:462301	21/65 (32%)
		Ion_trans_2	208..283	CDD:462301	21/79 (27%)