Protein Alignment CG42340 and Kcnk4

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: XP_006526780.1
• Gene: Kcnk4 / 16528
• MGIID: 1298234
• Length: 427
• Species: Mus musculus
• Alignment Length: 305
• Identity: 69/305 - (22%)
• Similarity: 103/305 - (33%)
• Gaps: 105/305 - (34%)

  Fly   226 GYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGGASG 290
            |||.|...|..||:..:.|||.|||:..:.|:.:|:.|.:.:|
Mouse   135 GYGNIVLHTDAGRLFCIFYALVGIPLFGMLLAGVGDRLGSSLR---------------------- 177

  Fly   291 GVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQQQ 355
                              :|.||.....| ::.:||
Mouse   178 ------------------RGIGHIEAIFL-KWHVPP----------------------------- 194

  Fly   356 VQQGKKSSGNRRGSPSVPISICVCVLLCYVSSGAILFHKLQNWSVLESLYFCFTSLGTIGFGEMA 420
                    |..|...:|...:..|:|  :|.:...:|..:::||.||::||...:|.|:|||:..
Mouse   195 --------GLVRSLSAVLFLLIGCLL--FVLTPTFVFSYMESWSKLEAIYFVIVTLTTVGFGDYV 249

  Fly   421 PNGAVALYTASAY-------ILVGMAVVAMCFSLIQTEIVLWLRRFSVQDH------VMPKAEEL 472
            |..... ..:.||       ||.|:|.    |:.:.|.|..|||..|.:..      ....|...
Mouse   250 PGDGTG-QNSPAYQPLVWFWILFGLAY----FASVLTTIGNWLRAVSRRTRAEMGGLTAQAASWT 309

  Fly   473 ALVTVAVT-------PKPSXQRPSADPSLGVGLGVGLAGGALGQP 510
            ..||..||       |.|. ::|....||.....|....|..|.|
Mouse   310 GTVTARVTQRTGPSAPPPEKEQPLLPSSLPAPPAVVEPAGRPGSP 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	15/37 (41%)
		Ion_trans_2	380..453	CDD:462301	23/79 (29%)
Kcnk4	XP_006526780.1	Ion_trans_2	<135..172	CDD:462301	15/36 (42%)
		Ion_trans_2	210..288	CDD:462301	26/84 (31%)
		PLN02983	<322..>374	CDD:215533	9/33 (27%)