Protein Alignment CG42340 and Kcnk3

DIOPT Version :10

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: NP_034738.1
• Gene: Kcnk3 / 16527
• MGIID: 1100509
• Length: 409
• Species: Mus musculus
• Alignment Length: 539
• Identity: 122/539 - (22%)
• Similarity: 189/539 - (35%)
• Gaps: 197/539 - (36%)

  Fly    90 KSHCISATGVLLLVLLYTAMGSIVFVTLEGELEDGGALETAVAASKPYPRTELANAEIRSRTVDR 154
            |...:....:::....|..:|:.||..||.|.|   .:|.        .|.||...|:|:|
Mouse     2 KRQNVRTLALIVCTFTYLLVGAAVFDALESEPE---MIER--------QRLELRQLELRAR---- 51

  Fly   155 LWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVYPPGGIQLNAPTHKWTYASAFLYSL 219
             ::::|.   .|:|                |.|.|.:.|.: ..|:|       |.:|.:|.:::
Mouse    52 -YNLSEG---GYEE----------------LERVVLRLKPH-KAGVQ-------WRFAGSFYFAI 88

  Fly   220 TLITTIGYGGISPRTQWGRVAALVYALFGIPIVLLYLSAMGEALSAGMRCLFRRQRVKGGPGGGP 284
            |:|||||||..:|.|..|:|..:.|||.|||:.|:...::||.::..:|.|..|
Mouse    89 TVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTFVRYLLHR----------- 142

  Fly   285 GGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQKLHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQ 349
               |..|:|
Mouse   143 ---AKRGLG-------------------------------------------------------- 148

  Fly   350 QAQQQQVQQGKKSSGNRRGSPSVPISICVCV-LLCYVSSGAILFHKLQNWSVLESLYFCFTSLGT 413
                  ::..:.|..|     .|.|....|: .||.   ||..|...:.|:..::.|:||.:|.|
Mouse   149 ------MRHAEVSMAN-----MVLIGFVSCISTLCI---GAAAFSYYERWTFFQAYYYCFITLTT 199

  Fly   414 IGFGE-MAPNGAVALYT-------ASAYILVGMAVVAMCFSLIQTEIVLWLRRFSVQDHVMPKAE 470
            ||||: :|.....||.|       :..|||.|:.|:....:|    :||.....:.:|. ...||
Mouse   200 IGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNL----VVLRFMTMNAEDE-KRDAE 259

  Fly   471 ELALVT-------------------VAVTPKPSXQRPSADPSLGVGLGVGLAGGALGQPQNNLGQ 516
            ..||:|                   ..|.|:.    |....:...|:|||:.|.........:..
Mouse   260 HRALLTHNGQAVGLGGLSCLSGSLGDGVRPRD----PVTCAAAAGGVGVGVGGSGFRNVYAEVLH 320

  Fly   517 HQTM---FFGPAHTLTQYS---SLPR----------RSHLQAANNSGGG------------SAFQ 553
            .|:|   .:..:....|||   .:||          .||   ::..|||            |..|
Mouse   321 FQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEHSH---SSPGGGGRYSDTPSHPCLCSGTQ 382

  Fly   554 RNTPIRRSTGIPEHHLEYF 572
            |:.....|||:  |.|..|
Mouse   383 RSAISSVSTGL--HSLAAF 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:462301	24/55 (44%)
		Ion_trans_2	380..453	CDD:462301	25/81 (31%)
Kcnk3	NP_034738.1	Ion_trans_2	<73..132	CDD:462301	26/65 (40%)
		Ion_trans_2	167..243	CDD:462301	26/82 (32%)