Protein Alignment CG42340 and Kcnk4

DIOPT Version :9

• Sequence 1: NP_001368973.1
• Gene: CG42340 / 7354472
• FlyBaseID: FBgn0259242
• Length: 759
• Species: Drosophila melanogaster
• Sequence 2: XP_006230696.1
• Gene: Kcnk4 / 116489
• RGDID: 621449
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 111/477 - (23%)
• Similarity: 166/477 - (34%)
• Gaps: 176/477 - (36%)

  Fly    74 EAGGGGGSLCGCQKAPKSHCISATGVLLLVLLYTAMGSIVFVTLE--------GELEDGGALETA 130
            :||.|.|...|  :|.:|..:.|  :|.|||||...|::||..||        .:||||     .
  Rat    14 QAGSGAGPAPG--RAMRSTTLLA--LLALVLLYLVSGALVFQALEQPHEQQVQKDLEDG-----R 69

  Fly   131 VAASKPYPRTELANAEIRSRTVDRLWSITEDLNILYKENWTRLAAQEVQLFQDTLLRAVRQSKVY 195
            ....|.:|.....|.                      |.:.:|.|:.:
  Rat    70 DQFLKDHPCVSQKNL----------------------EGFIKLVAEAL----------------- 95

  Fly   196 PPGGIQ-----LNAPTHK--WTYASAFLYSLTLITTIGYGGISPRTQWGRVAALVYALFGIPIVL 253
             .||..     .|:..|.  |...|||.:|.|:|||||||.|:..|..||:..:.|||.|||:..
  Rat    96 -GGGANPETSWTNSSNHSSAWNLGSAFFFSGTIITTIGYGNIALHTDAGRLFCIFYALVGIPLFG 159

  Fly   254 LYLSAMGEALSAGMRCLFRRQRVKGGPGGGPGGGASGGVGSGAGGSGGGRKTDKNKGQGHYGHQK 318
            :.|:.:|:.|.:.:|                                        :|.||.....
  Rat   160 MLLAGVGDRLGSSLR----------------------------------------RGIGHIEAVF 184

  Fly   319 LHQYGLPPSVYQQQQAQQAQQAQQQQAQQAQQAQQQQVQQGKKSSGNRRGSPSVPISICVCVLLC 383
            | ::.:||.:.:...|                                     |...:..|:|
  Rat   185 L-KWHVPPGLVRMLSA-------------------------------------VLFLLIGCLL-- 209

  Fly   384 YVSSGAILFHKLQNWSVLESLYFCFTSLGTIGFGEMAPNGAVALYTASAY-------ILVGMAVV 441
            :|.:...:|..:::||.||::||...:|.|:|||:..|..... ..:.||       ||.|:|.
  Rat   210 FVLTPTFVFSYMESWSKLEAIYFVIVTLTTVGFGDYVPGDGTG-QNSPAYQPLVWFWILFGLAY- 272

  Fly   442 AMCFSLIQTEIVLWLRRFSVQDH------VMPKAEELALVTVAVT-------PKPSXQRPSADPS 493
               |:.:.|.|..|||..|.:..      ....|.....||..||       |.|. ::|....|
  Rat   273 ---FASVLTTIGNWLRAVSRRTRAEMGGLTAQAASWTGTVTARVTQRTGPSAPPPEKEQPLLPSS 334

  Fly   494 LGVGLGVGLAGGALGQPQNNLG 515
            |.       |..|:.:|.:..|
  Rat   335 LP-------APPAVAEPAHRPG 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42340	NP_001368973.1	Ion_trans_2	<208..264	CDD:400301	25/57 (44%)
		Ion_trans_2	380..453	CDD:400301	23/79 (29%)
Kcnk4	XP_006230696.1	Ion_trans_2	<115..169	CDD:285168	25/53 (47%)
		Ion_trans_2	207..285	CDD:285168	26/84 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349044
Domainoid	1	1.000	66	1.000	Domainoid score	I9664
eggNOG	1	0.900	-	-		E1_KOG1418
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11003
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840