Protein Alignment CG42342 and Col18a1

DIOPT Version :9

• Sequence 1: NP_001189234.1
• Gene: CG42342 / 7354466
• FlyBaseID: FBgn0259244
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: NP_445941.2
• Gene: Col18a1 / 85251
• RGDID: 70936
• Length: 1311
• Species: Rattus norvegicus
• Alignment Length: 726
• Identity: 248/726 - (34%)
• Similarity: 299/726 - (41%)
• Gaps: 245/726 - (33%)

  Fly   218 QAAEAAAAAASGEGGSGG--GQCQCQP---------GPPGPPGPPGKRGKRGKKGDSGEKGDPGL 271
            |..|..|....|..|..|  |.....|         |||||.|||||.|..|:.|:.|:.|:.|.
  Rat   331 QKGEPGAQGPPGPAGPQGPAGPAVQSPSSQPVPGAQGPPGPQGPPGKDGIPGRDGEPGDPGEDGR 395

  Fly   272 NGISGEKGAAGKPGDKGQKGDVGHPGMD--------------------VFQTVKGLKRSVTTLHG 316
            .|.:|.:|..|.|||.|.||:.|.||:.                    .|..::|        .|
  Rat   396 PGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPPGPPGPSFRQDKLTFIDMEG--------SG 452

  Fly   317 GTLGYAEIVAVKDLQEAGVNVSASTVIKLKGEPGEPGPPGP--------------------PGEA 361
            |..|        ||:            .|:|..|.||||||                    ||.|
  Rat   453 GFSG--------DLE------------SLRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSYAPGPA 497

  Fly   362 GQPGAPGERGPPGEIGAQGPQGEAGQPGVAGPPGV---AGAPGTKGDKGDRGDRGL--TTTIKGD 421
            |.||.||:.||||..|..||.|:.|.|||||..|.   ||:||.||.|||.|..|:  .:.:.|.
  Rat   498 GLPGVPGKEGPPGFPGPPGPPGKEGPPGVAGQKGSVGDAGSPGPKGSKGDLGPIGMPGKSGLPGL 562

  Fly   422 EFPTGIIEGPPGPAGPPGPP-----------------------------------GEPGARGE-- 449
            ..|.    |||||.||||||                                   |.|||:||
  Rat   563 PGPV----GPPGPPGPPGPPGPGFAAGFDDMEGSGTPLWSTARSSDGLQGDPGVTGPPGAKGEVG 623

  Fly   450 ----------PGPIGPAGPPGEKGPRGKRGKR-------IFGPGGTKIDEDYDDPPVTLLRGPPG 497
                      ||..|.|||||.||.:|.:|::       :..||               |.||||
  Rat   624 ADGVQGIPGLPGREGVAGPPGPKGEKGTQGEKGNPGKDGVGRPG---------------LPGPPG 673

  Fly   498 PPG----IAGKD-------GRDGRDGSKGEPGEPGEPGSLGPRGLDGLPGEPGIEGPPG------ 545
            |||    ::.:|       |.:|:.|..|.||..|..|.||.:|..||||..|.:|.||
  Rat   674 PPGPVIYVSNEDRAVVSTPGPEGKPGYAGFPGPAGPKGDLGSKGEQGLPGPKGEKGEPGSIFSPD 738

  Fly   546 -------LPGYQGPPGEKGDRGDIGPPGLMGPPGLPGPPGYPGVKGDKGDRGDSYRKMRRRQDDG 603
                   ..|.:|.||.:|..|..|.||..|..|.||.||.||..|.||::|:.
  Rat   739 GTALGQAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGTNGLKGEKGEP----------- 792

  Fly   604 MSDAPHMPTIEYLYGPPGPPGPMGPPGHTGSQGERGLDGRKGDPGEKGHKGDQGPMGLPGPMGMR 668
             .:|....::..|.||||||||.||||.........::  .|.||..|.:|.|||   |||.|.:
  Rat   793 -GEASLGFSMRGLPGPPGPPGPPGPPGVPVYDSNAFVE--SGRPGLPGQQGVQGP---PGPKGDK 851

  Fly   669 GESGPSGPSGKAGIPGPPG------------LDGMKGAQGETGHKGERGDPGL------------ 709
            ||.||         |||||            :.|.||.:|:.|.|||||:||.
  Rat   852 GEVGP---------PGPPGQFPIDLFHLEAEMKGDKGDRGDAGRKGERGEPGAPGGGFFSSSVPG 907

  Fly   710 -PGTDGIPGQEGPRGEQGSRGDAGPPGKRGRKGDRGDKGEQGVPGLDAPCPLGADGLP-LPGCGW 772
             ||..|.||..||:|| ..||..||||.:|..| .|.:|.||.||     |.|..|.| .||
  Rat   908 PPGPPGYPGIPGPKGE-SIRGPPGPPGPQGPPG-IGYEGRQGPPG-----PPGPPGPPSFPG--- 962

  Fly   773 RPPKEPIISTP 783
              |....:|.|
  Rat   963 --PHRQTVSVP 971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42342	NP_001189234.1	DUF4763	130..>210	CDD:292582
		Collagen	366..413	CDD:189968	27/49 (55%)
		Collagen	660..718	CDD:189968	29/82 (35%)
		Collagen	690..748	CDD:189968	30/70 (43%)
Col18a1	NP_445941.2	TSPN	33..221	CDD:214560
		Collagen	<381..416	CDD:189968	14/34 (41%)
		Collagen	605..659	CDD:189968	18/53 (34%)
		Collagen	<692..733	CDD:189968	18/40 (45%)
		Endostatin-like	1135..1304	CDD:238151

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000