Protein Alignment CG42342 and Col25a1

DIOPT Version :10

• Sequence 1: NP_001189234.1
• Gene: CG42342 / 7354466
• FlyBaseID: FBgn0259244
• Length: 831
• Species: Drosophila melanogaster
• Sequence 2: XP_006502327.1
• Gene: Col25a1 / 77018
• MGIID: 1924268
• Length: 707
• Species: Mus musculus
• Alignment Length: 802
• Identity: 303/802 - (37%)
• Similarity: 371/802 - (46%)
• Gaps: 215/802 - (26%)

  Fly    85 ISNNSSNSSSSKERPRP-------TVRFISLLHVASYVLCLCAFSFALYGNVRQTRLEQRMQRLQ 142
            ::.......|..|.|||       |:...:.|   :.:|.:.|.:|..|..|          :..
Mouse     6 LAGKGGGRESGSEDPRPLGQRCAGTMPSCTAL---ATLLSVVAVAFCFYLGV----------KTN 57

  Fly   143 QLDARIVELELRLEQQQLLHWPAEQTQVLASHP-SDRDSSNSNNGSQHLELHVRRELHRLRRDVS 206
            .|.|||..||           .|:.|.  :.|| ||.        ...|:..|:.::.||....|
Mouse    58 DLQARIAALE-----------SAKGTP--SFHPLSDT--------VDELKAMVQEKVERLLAQKS 101

  Fly   207 HLQLTRRQQRRQAAEAAAAAASGEGGSGGGQCQCQPGPPGPPGPPGKRGKRGKKGDSGEKGDPGL 271
            :..:.:.:..|:|..               :|.|      |.||||||||||::|:||..|.||.
Mouse   102 YEHMAKIRTAREAPL---------------ECNC------PAGPPGKRGKRGRRGESGPPGQPGP 145

  Fly   272 NGISGEKGAAGKPGDKGQKGDVGHPGMDVFQTVKGLKRSVTTLHGGTLGYAEIVAVK----DLQE 332
            .|..|.|      ||||::||.| |.| ||..:.         ||......:::..:    |..:
Mouse   146 QGPPGPK------GDKGEQGDQG-PRM-VFPKIN---------HGFLSADQQLIKRRLIKGDQGQ 193

  Fly   333 AGVNVSASTVIKLKGEPGEPGPPGPPGEAGQ------PGAPGERGPPGEIGAQGP---------- 381
            ||.          .|.||.|||.||||:.|:      ||.|||.|.|||.|..||
Mouse   194 AGP----------PGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSI 248

  Fly   382 -----------QGEAGQPGVAGP---PGVAGAPGTKGDKGDRGDRGL--TTTIKGDEFPTGI-IE 429
                       :||.|.||.||.   ||..|.||.:|:|||.|:.|.  .|..|||...:.. |:
Mouse   249 GAPGTPGMDGQKGEPGSPGAAGQSGLPGPKGEPGKEGEKGDAGENGPKGDTGEKGDPGSSAAGIK 313

  Fly   430 GPPGPAGPPGPPGEPGARGEPGPIGPAGPPGEKGPRGKRGKRIFGPG--GTKIDEDYDDPPVTLL 492
            |.||.:|.||..||||..|.||..|..|.||..||:|:.|.    ||  |||.|.....||....
Mouse   314 GEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGL----PGLPGTKGDRGEAGPPGRGE 374

  Fly   493 RGPPGPPGIAGKDGRDGR---DGSKGEPGEPGEPGSLGPRGLDGLPGEPG--------------- 539
            ||.||.||..||.|..|.   .||||:.|:.|:.|:|||||..|..|:||
Mouse   375 RGDPGAPGPKGKQGESGARGPKGSKGDRGDKGDSGALGPRGPPGQKGDPGATEIIDYNGNLHEAL 439

  Fly   540 -------IEGPPGLP---GYQGPPGE------------------KGDRGDIGPPGLMGPPGLPGP 576
                   :.||||.|   |.|||.||                  |||.||.|.||..|..||||.
Mouse   440 QRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGVDGEQGLKGSKGDMGDPGVPGEKGGLGLPGL 504

  Fly   577 PGYPGVKGDKGDRGDSYRKMRRRQDDGMSDAPHMPTIEYLYGPPGPPGPMGPPG----H--TGSQ 635
            ||..||||:|||.|              ...|..|:|   .||||||||.||||    |  .|.:
Mouse   505 PGANGVKGEKGDTG--------------LPGPQGPSI---IGPPGPPGPHGPPGPMGPHGLPGPK 552

  Fly   636 GERGLDGRKGDPGEKGHKGDQGPMGLPGPMGM------RGESGPSGPSGKAGIPGPPGLDGMKGA 694
            ||.||:|.||..||.|.|||:||:||||..|:      ||..||.||.|.|   ||.|..|.|||
Mouse   553 GEPGLNGVKGLKGEPGQKGDRGPLGLPGASGLDGKPGSRGADGPIGPHGPA---GPKGERGEKGA 614

  Fly   695 QGETGHKGERGDPGL---PGTDGIPGQEGPRGEQGSRGDAGPPGKRGRKGDRGDKGEQGVPGLDA 756
            .||.|.:|..|.||.   ||.||.||..|.:|:.|.:|:.|..||:|::|.:|:|||||.|||||
Mouse   615 MGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGEKGKKGKRGPKGEKGEQGAPGLDA 679

  Fly   757 PCPLGADGLPLPGCGWRPPKEP 778
            |||||.||||:||| |:....|
Mouse   680 PCPLGPDGLPMPGC-WQKGVTP 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42342	NP_001189234.1	DUF2046	<133..210	CDD:401633	17/77 (22%)
		gly_rich_SclB	<249..>413	CDD:468478	75/197 (38%)
		gly_rich_SclB	<368..>560	CDD:468478	101/266 (38%)
		gly_rich_SclB	<527..>757	CDD:468478	126/287 (44%)
Col25a1	XP_006502327.1	Collagen	216..271	CDD:460189	18/54 (33%)
		gly_rich_SclB	<257..>495	CDD:468478	96/241 (40%)
		gly_rich_SclB	<371..>634	CDD:468478	119/282 (42%)