DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42395 and CG4686

DIOPT Version :9

Sequence 1:	NP_001138182.3	Gene:	CG42395 / 7354436	FlyBaseID:	FBgn0259741	Length:	179	Species:	Drosophila melanogaster
Sequence 2:	NP_001262744.1	Gene:	CG4686 / 42361	FlyBaseID:	FBgn0038739	Length:	181	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	125/179 - (69%)
Similarity:	152/179 - (84%)	Gaps:	0/179 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAETLHYLILRNPSSQIVIASANAVLESIGLENWKIPVDDSIVSLPPSAQSYVHSHSSLYCLAGC 65
            :|:|:.|:.|.||.|::|.:||:|:|.::||...|:||.::.:::.|:|.||.|||.|||.||||
  Fly     3 VADTIEYVTLGNPVSKMVASSASALLRTLGLRPKKVPVQETSMAVLPAAHSYAHSHGSLYRLAGC 67

  Fly    66 HYHFMRLAGIGGASAIFMSAYCKYVLRDIESIREQLDSQAFADVANRIHFLHSFALMAMPLAHYP 130
            ||||:|||||.|||||||.|||||||:|:...:||:|||||||||||||||||||:|||||||||
  Fly    68 HYHFIRLAGIVGASAIFMGAYCKYVLKDVSDPKEQVDSQAFADVANRIHFLHSFAMMAMPLAHYP 132

  Fly   131 FLTGTLMITGTLAFSGSMYYRALTGEKWMQPYATMGGFCLMAAWLSLVL 179
            ..||||||||.:.|||.||||||||||.:|||||:||||||||||||||
  Fly   133 VFTGTLMITGMMLFSGCMYYRALTGEKRLQPYATVGGFCLMAAWLSLVL 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42395	NP_001138182.3	DUF423	83..168	CDD:282144	66/84 (79%)
CG4686	NP_001262744.1	ribokinase_pfkB_like	<24..114	CDD:294126	57/89 (64%)
CG4686	NP_001262744.1	DUF423	85..170	CDD:282144	66/84 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470063
Domainoid	1	1.000	44	1.000	Domainoid score	I4692
eggNOG	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H136232
Inparanoid	1	1.050	62	1.000	Inparanoid score	I2534
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1632823at2759
OrthoFinder	1	1.000	-	-		FOG0005087
OrthoInspector	1	1.000	-	-		otm26361
orthoMCL	1	0.900	-	-		OOG6_102451
Panther	1	1.100	-	-	P	PTHR43461
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4384
SonicParanoid	0	0.000	Not matched by this tool.
	10	10.020