Protein Alignment OtopLc and Otop3

DIOPT Version :9

• Sequence 1: NP_001303575.1
• Gene: OtopLc / 7354434
• FlyBaseID: FBgn0259150
• Length: 1596
• Species: Drosophila melanogaster
• Sequence 2: XP_038941598.1
• Gene: Otop3 / 287821
• RGDID: 1306663
• Length: 578
• Species: Rattus norvegicus
• Alignment Length: 685
• Identity: 140/685 - (20%)
• Similarity: 251/685 - (36%)
• Gaps: 182/685 - (26%)

  Fly   825 PDSSDPPSSPGGSSSQPALSGSQADGQLALMYHSHQLTNYPVLPAIK---RTHRPSFVYPPMPRV 886
            |:.:..|||. ..:::.|.:..||:..:...:     |..|..|..|   ..|....:.......
  Rat     8 PEPAPMPSSE-AETTEAASTYDQANMDVETKH-----TGPPGAPKQKSWLALHFSLLLRRDRQAQ 66

  Fly   887 KAGDALATLFSALYGKLLVVMGIAFPMAEVISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWG 951
            |||.    |||.|....:|.:|.|| :..:|...:..:..:|:.|...:..:..|..:|.|:
  Rat    67 KAGQ----LFSGLLALNVVFLGGAF-ICSMIFNKVAVTLGDVWILLAALKVLSLLWLLYYTV--- 123

  Fly   952 RPKLPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHYGSFYL 1016
                               ||                      .|:|..:.   .||.|.|..::
  Rat   124 -------------------GT----------------------TRKPHAVL---YRDPHAGPVWV 144

  Fly  1017 RMGAVAFGIGSMIYSGLEFGQYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLN-NEQIKVY 1080
            |...|.||..::..:....|  :::: ...|.:.:..:.||..:.|:.||.:.::.: .:.::|.
  Rat   145 RGSLVLFGSCTVCLNVFRMG--YDVS-HIHCKSEVELIFPAIEIVFMIIQTWVLWKHCKDCVQVQ 206

  Fly  1081 RYKIIARFGLMHMIGTNLAVWLNVLIQETKHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPT 1145
            ..  ..|.|||..:.|||.:|:..:..::.|..:     |.....:..:..|:.....:
  Rat   207 TN--FTRCGLMLTLATNLLMWVLAVTNDSMHREI-----EAELDALMEKFSGNGTNTCM------ 258

  Fly  1146 AHLRVPRGLKGPYQIFECRRTNII-----GTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRP 1205
                             |....:.     |.|:      |:|.:.||.|||.|:|:|||:::.|.
  Rat   259 -----------------CLNATVCEVFRKGFLM------LYPFSTEYCLICCAVLFVMWKNVGRS 300

  Fly  1206 ----QTPTPQRPDMISSPMKRSPHHYSVDCARAHKGLF---VGILILVLTIISLIIFFVLISRPE 1263
                ....|.||..                 |.|..:|   :|:|.||..:...::|.:..|.|:
  Rat   301 LAAHSGAHPNRPPF-----------------RLHGAIFGPLLGLLALVAGVCVFVLFQIEASGPD 348

  Fly  1264 FVAMAVTEVTICELLIYGTATIATLVGM----IQIRHLQYDAYRSFSLDDILLVGAQTGSFLYNI 1324
            ......|......:.:..|.::|.|.|.    ::.|.|......:.|||.:||:||..|......
  Rat   349 IARQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTLKNPTRSLDVVLLMGAALGQMGIAY 413

  Fly  1325 FTVIA-----GHFTLRSDDMLVPINALASIVQTACQTMFILD----------------------- 1361
            |:::|     .|..|   :.|:...:|..|:|...|.:||::
  Rat   414 FSIVAIVATQPHQLL---NQLILAYSLLLILQHITQNLFIIEGLHRRPLWEPVISGVPEKQDIEL 475

  Fly  1362 ---------------ASRRQAVSPEHL--RKKPGREIVTFMLVVNLAMWAISTLEKSRAESHPIQ 1409
                           |||....|..||  :::..:||..|:::.|:.:|.:..........:.::
  Rat   476 PRRGSLRELGQDLRRASRAYIHSFSHLNWKRRMLKEISLFLILCNITLWMMPAFGIHPEFENGLE 540

  Fly  1410 LNFYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIW 1444
            .:|||...|..|.:..:||.:|||.||...|.|::
  Rat   541 KDFYGYRTWFTIVNFGLPLGVFYRMHSVGGLVEVY 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLc	NP_001303575.1	Otopetrin	1015..1434	CDD:281218	98/480 (20%)
Otop3	XP_038941598.1	Otopetrin	149..564	CDD:397346	96/473 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR21522
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	5.020