Protein Alignment OtopLc and otpl-6

DIOPT Version :10

• Sequence 1: NP_001303575.1
• Gene: OtopLc / 7354434
• FlyBaseID: FBgn0259150
• Length: 1596
• Species: Drosophila melanogaster
• Sequence 2: NP_505195.1
• Gene: otpl-6 / 185807
• WormBaseID: WBGene00018479
• Length: 581
• Species: Caenorhabditis elegans
• Alignment Length: 650
• Identity: 160/650 - (24%)
• Similarity: 285/650 - (43%)
• Gaps: 167/650 - (25%)

  Fly   861 LTNYPV-----LPA-IKRTHRPSFVYPPMPRVKAGDALATLFSALYGKLLVVMGIAFPMAEVIST 919
            ||:|..     ||| .|.|...||            .|.:| :|||..:|.:  :|| :.|:..|
 Worm    23 LTDYSSTIPENLPAWTKNTKAQSF------------GLKSL-TALYTLILTI--VAF-IIEISPT 71

  Fly   920 YIPPSF---YEVYYLYLYIGSMIFLLFMYATLIWGRPKLPVPIASPSKSATKASGTDSMDESDTD 981
            :...|.   |.::.:.:|..::::.:::||.:::       ||         ...|..:......
 Worm    72 WQSESMNIEYTIFCVLMYSIAILYFIYLYAYILY-------PI---------VFNTILLYLERMR 120

  Fly   982 SNSVH--HRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMGAVAFG-IGSMIYSGLEFGQYFELNP 1043
            ..:||  .|...|.||     .:..|.     |:.|||:|.|.|| :||:::....|..:|   .
 Worm   121 VLNVHTVKRWVQPEPV-----FTGEGA-----GTLYLRLGTVLFGTLGSVLWGCEIFLCFF---T 172

  Fly  1044 DTKCHNV-----LLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKIIARFGLMHMIGTNLAVWLN 1103
            :|: ||:     :||      ..|.::||:|:..|: :|.:.:...:|.||:||.:..||.||.:
 Worm   173 ETR-HNIYVVKYILA------FLFTYLQMHFLCCNS-KIDLPKNNFLASFGMMHCVAVNLWVWFS 229

  Fly  1104 VLIQETKHEILTFYNPENRTLRISHRIPGHSRGH----------------AIIQHDPTAHLRV-P 1151
            :.:.:      ..|..:.:||::......:.:.:                :|:..:.::..|. .
 Worm   230 LCLAK------AVYKSDKKTLKLQKAEEKYKKKNMTITEAVAETITTTIASIVSSESSSGFRADE 288

  Fly  1152 RGLKGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMI 1216
            :.|:..|::             ..|:.||....:|:|||.||:.:::|:. ...|||...|
 Worm   289 KQLRSLYKL-------------GSAANFLLTTMVEFSLIAAAVYFIVWKH-EGEQTPQDAR---- 335

  Fly  1217 SSPMKRSPHHYSVDCARAHKGLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYG 1281
                   ..|...||.....|:|..|::|:.:.||:.:.:: .:..:....|...:.|.|.:::.
 Worm   336 -------KKHVRFDCKSTSVGIFAAIVLLIGSFISIAMHYI-YNNSDMPRTADEVIGIAETVLFC 392

  Fly  1282 TATIATLVGMIQIRHLQYDAY-RSFSLDDILLVGAQTGSFLY-------------------NIFT 1326
            ...:|.....|::|.|||..: ....:|:|||:....|..:|                   :..|
 Worm   393 VCLLAVFGAFIRMRKLQYRLHAHGQVVDEILLIVGLAGEIVYCSTGLDLYLNGRLENTPGTSCLT 457

  Fly  1327 VIAGHFTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRKKPGREIVTFMLVVNLA 1391
            |:|  |.:|             |||...|::|||.|||.:::|..::..:||::||||::|.|:.
 Worm   458 VVA--FVMR-------------IVQVVVQSVFILVASRLRSLSASNISNQPGKQIVTFLVVCNIN 507

  Fly  1392 MWAISTLEKSRAESHPIQLNFYGL-----WAWTIITHVSMPLAIFYRFHSTVCLCEIWKRAYKLK 1451
            ::...|.|       .|:.|| |.     ..::.:.::|.||.:||||||:.||.||||.||..|
 Worm   508 LFIYHTFE-------TIESNF-GFPHKMSSVYSALLNISSPLVVFYRFHSSACLAEIWKHAYSKK 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLc	NP_001303575.1	Retinal	<442..643	CDD:464722
		Otopetrin	1015..1434	CDD:460840	111/466 (24%)
otpl-6	NP_505195.1	Otopetrin	146..547	CDD:460840	111/466 (24%)