Protein Alignment OtopLc and otpl-2

DIOPT Version :9

• Sequence 1: NP_001303575.1
• Gene: OtopLc / 7354434
• FlyBaseID: FBgn0259150
• Length: 1596
• Species: Drosophila melanogaster
• Sequence 2: NP_001309627.1
• Gene: otpl-2 / 183919
• WormBaseID: WBGene00017034
• Length: 576
• Species: Caenorhabditis elegans
• Alignment Length: 594
• Identity: 149/594 - (25%)
• Similarity: 267/594 - (44%)
• Gaps: 140/594 - (23%)

  Fly   897 SALYGKLLVVMGIAFPMAEVISTYIPPSF---YEVYYLYLYIGSMIFLLFMYATLIWGRPKLPVP 958
            ||||..:|.:  ||| :.|:..|:.....   |.::.:.:|:.::::..:.|..:|:  |.:
 Worm    57 SALYALILTM--IAF-VIEISPTWRSQEMWLEYSIFGVLMYLFAILYFTYFYLFVIY--PNI--- 113

  Fly   959 IASPSKSATKASGTDSMDESDTDSNSV---HHRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMGA 1020
                                   .||:   .||......:.|..|..|:...:. .|:.|||:|.
 Worm   114 -----------------------INSIIYFLHRRGRIASLHRWLLEEPVFNGEG-AGTMYLRIGT 154

  Fly  1021 VAFG-IGSMIYSGLEFGQYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKI 1084
            :.|| :|:::|.......:|    ||: .|.:........:|||::||:||| :|.::.:.....
 Worm   155 LFFGSMGAVLYITEILLCFF----DTQ-RNGIYVTKYTLAVAFIYMQMHFIF-SNSKVLLKSSNA 213

  Fly  1085 IARFGLMHMIGTNLAVWLNVLI---------QETKH--EILTFYNPENRTLRISHRIPGHSRGHA 1138
            ||:|||||.:..||..||::.:         :|.||  :.|......|...:.|:.:..:|.|
 Worm   214 IAKFGLMHSVAVNLWTWLSICLIKSDMKHSKKEMKHAEDGLKNQTATNVLAQWSYNLTTNSFG-- 276

  Fly  1139 IIQHDPTAHLRVPRGLKGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSIS 1203
              .||......|..|                     .::..|..|.:|:|||.|.|.:::|::
 Worm   277 --AHDKQLRTIVKMG---------------------SSANLLLTCLVEFSLIAAVICFIIWKN-- 316

  Fly  1204 RPQTPTPQRPDMISSPMKRSPHHYSVDCARAHKGLFVGILILVLTIISLIIFFVLI-SRPEFVA- 1266
              ..|.|...:  ..|.|:|   ...||.....|||..|.|.:::::.:.:..:.: ...|.||
 Worm   317 --DHPNPGNSE--KKPKKQS---VRFDCNGTSVGLFTAIFIHIISVVVIGLHGIYMKDHNEKVAD 374

  Fly  1267 --MAVTEVTICELLIYGTATIATLVGMIQIRHLQYDAY-RSFSLDDILLVGAQTGSFLYN----- 1323
              :..|:|.:..:|::     |.|:.:.|:|.|||.:: ....:|||||:....|..:|:
 Worm   375 QLIGYTDVLMFVILLF-----ACLLALFQMRKLQYTSHVHGEVIDDILLIVGLAGECVYSCAAID 434

  Fly  1324 -------------IFTVIAGHFTLRSDDMLVPINALASIVQTACQTMFILDASRRQAVSPEHLRK 1375
                         ..|:||  |:||..:::|             ||:|||.|:|.:: ||.. .|
 Worm   435 LYVNEKLMDRPVPYITMIA--FSLRITEVIV-------------QTLFILIAARMRS-SPLS-NK 482

  Fly  1376 KPGREIVTFMLVVNLAMWAISTLEKSRAE-SHPIQLNFYGLWAWTIITHVSMPLAIFYRFHSTVC 1439
            :||::::||:|:.|:.::...|.|.:.:. ..|.:::    ..:|::..::.|:.:||||||:.|
 Worm   483 QPGKQVITFLLICNINLFIYHTFETTESSFGFPAKVS----EVYTVMLTIASPIVVFYRFHSSAC 543

  Fly  1440 LCEIWKRAY 1448
            |.||||..|
 Worm   544 LAEIWKNTY 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLc	NP_001303575.1	Otopetrin	1015..1434	CDD:281218	115/454 (25%)
otpl-2	NP_001309627.1	Otopetrin	149..538	CDD:281218	115/454 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	175	1.000	Domainoid score	I2171
eggNOG	1	0.900	-	-		E1_KOG4740
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	1	1.000	-	-		FOG0001932
OrthoInspector	1	1.000	-	-		mtm4740
orthoMCL	1	0.900	-	-		OOG6_105319
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.680