Protein Alignment OtopLc and otop2

DIOPT Version :9

• Sequence 1: NP_001303575.1
• Gene: OtopLc / 7354434
• FlyBaseID: FBgn0259150
• Length: 1596
• Species: Drosophila melanogaster
• Sequence 2: XP_017944835.2
• Gene: otop2 / 100496174
• XenbaseID: XB-GENE-6045877
• Length: 588
• Species: Xenopus tropicalis
• Alignment Length: 673
• Identity: 146/673 - (21%)
• Similarity: 251/673 - (37%)
• Gaps: 225/673 - (33%)

  Fly   879 VYPPMP---RVKAGDALAT-------------LFSALYGKLLVVMGIAFPMA-----------EV 916
            |.||.|   ::..|:..|.             |.|.|.|..:|::|.|...:           ||
 Frog    31 VPPPDPTFEKISLGELSAVSAKSPEVWKKGGRLLSGLLGINIVLLGCALVSSGAFTDVSVAEREV 95

  Fly   917 ISTYIPPSFYEVYYLYLYIGSMIFLLFMYATLIWGRPKLPVPIASPSKSATKASGTDSMDESDTD 981
            :|           :|.:.:|  :..::|.:.|:|
 Frog    96 LS-----------FLSVLMG--LSSIWMVSYLLW------------------------------- 116

  Fly   982 SNSVHHRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMGAVAFGIGSMIYSGLEFGQYFELNPDTK 1046
             .|.|                ....:|:|.|..:||.|.|.||:.:::...::.|:...|   ..
 Frog   117 -TSKH----------------KYNLKDSHAGPIWLRGGLVLFGVCTLVLDVMKIGKSVTL---IH 161

  Fly  1047 CHNVLLALTPATRMAFIFIQMYFIFLNNE---QIKVYRYKIIARFGLMHMIGTNLAVWLNVLIQE 1108
            |.:.:..:.|..:..|:.||.||::::.:   ||    :..:.|.|||..:.||||||:..:..|
 Frog   162 CESPVKIVHPVIQGVFVVIQTYFLWVSCKDCAQI----HMNLTRCGLMITLSTNLAVWMAAVTDE 222

  Fly  1109 TKHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPTAHLRVPRGLKGPYQIFECRRTNIIGTLV 1173
            :.|              ::|.:      :..:.:..:|.:. ||...|.....|| .|::..|.
 Frog   223 SLH--------------LTHEL------NMDVNYTVSATVG-PRAAGGESHGCEC-ATHVCKTF- 264

  Fly  1174 QDASPFLFPCTIEYSLICAAILYVMWRSISRPQTPTPQRPDMISSPMKRSPHHYSVDCARAHK-- 1236
            |:...:|:|..|||||..:|:.||||:::.|..                |.||::     .||
 Frog   265 QNGYYYLYPFNIEYSLFASAMSYVMWKNVGRVM----------------SGHHHT-----QHKFK 308

  Fly  1237 ------GLFVGILILVLTIISLIIFFVLISRPEFVAMAVTEVTICELLIYGTATIATLVGMIQIR 1295
                  ||..||.:.|..:...|::.:.:...|..:.|:|...|..:......::.:|.|.|..|
 Frog   309 TRNLFVGLICGIGVFVAGLGVFIVYKIEVDVEETRSQAITMFYIFNITALSLMSVVSLAGTIIYR 373

  Fly  1296 HLQYDAYR----SFSLDDILLVGAQTGSFLYNIFTVIA-------GHFTLRSDDMLVPINALASI 1349
            ..:.|...    :.:||.:||:||..|.:..:.|:::|       |..     ..|:.:|||..|
 Frog   374 FYKRDMDNHKNPTRTLDVVLLLGAALGQYCISFFSIVAMVALQPGGQL-----HTLILVNALLLI 433

  Fly  1350 VQTACQTMFILDASRRQAVS-------------PEHL---------------------------- 1373
            ||...|..||::...||..:             |.|:
 Frog   434 VQHTIQNTFIIEGLHRQPHANSHPAADLQEKDQPPHVYINPAATVSHSDHSPSSHEKHEHELETK 498

  Fly  1374 -----------------RKKPGREIVTFMLVVNLAMWAISTLEKSRAESHPIQLNFYGLWAWTII 1421
                             |:|..:||..|:||.|:..|.:..........:.::||||| :.|..|
 Frog   499 HHGTPTGFPECHSKSDWRRKALKEISLFLLVSNIIFWIMPAFGARPQFDNRLELNFYG-YTWVAI 562

  Fly  1422 THVSMPLAIFYRFHSTVCLCEIW 1444
            .::.:|..||||.|:...|.|::
 Frog   563 VNIGLPFGIFYRMHAIASLVEVY 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLc	NP_001303575.1	Otopetrin	1015..1434	CDD:281218	116/498 (23%)
otop2	XP_017944835.2	Otopetrin	134..574	CDD:397346	115/496 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H27803
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9424
Panther	1	1.100	-	-	LDO	PTHR21522
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.020