Protein Alignment OtopLc and otop3

DIOPT Version :9

• Sequence 1: NP_001303575.1
• Gene: OtopLc / 7354434
• FlyBaseID: FBgn0259150
• Length: 1596
• Species: Drosophila melanogaster
• Sequence 2: NP_001106584.1
• Gene: otop3 / 100127796
• XenbaseID: XB-GENE-993899
• Length: 681
• Species: Xenopus tropicalis
• Alignment Length: 692
• Identity: 133/692 - (19%)
• Similarity: 243/692 - (35%)
• Gaps: 262/692 - (37%)

  Fly   895 LFSALYGKLLVVMGIAFPMAEVISTYIPP-----SFYEVYYLYLYIGSMIFLLFMYATLIWGRPK 954
            |||.|:|..|:.:|.....:..:|....|     ||..:..|...:.::..|||:
 Frog   113 LFSGLFGLNLMFLGGTVVSSVALSNKAVPERDSQSFLCILMLLSSVWALYHLLFI---------- 167

  Fly   955 LPVPIASPSKSATKASGTDSMDESDTDSNSVHHRLPPPIPVRRPSLLSPLGRRDAHYGSFYLRMG 1019
                                    ...:.:|||                    |.|.|:.:|:..
 Frog   168 ------------------------RNQNGAVHH--------------------DHHAGAMWLKAS 188

  Fly  1020 AVAFGIGSMIYSGLEFGQYFELNPDTKCHNVLLALTPATRMAFIFIQMYFIFLNNEQIKVYRYKI 1084
            ...||:.|:|.|..|.|....|.   .|..::..:..:..:.|:.:|...::::.:.. |..:..
 Frog   189 LAIFGVCSIILSIFEIGHALLLQ---NCEILMDIVFFSIEIVFVSVQTVLLWVSCKDC-VQMHHS 249

  Fly  1085 IARFGLMHMIGTNLAVWLNVLIQETKHEILTFYNPENRTLRISHRIPGHSRGHAIIQHDPT---- 1145
            :.|:|:|..:.|::.:||..:|.::..:.|                       .|:|.:.|
 Frog   250 VTRYGIMLTLATDILLWLTAVIDDSLEQDL-----------------------EILQSNSTQDES 291

  Fly  1146 ---AHLRVPR-----GLKGPYQIFECRRTNIIGTLVQDASPFLFPCTIEYSLICAAILYVMWRSI 1202
               |..:.|.     |||..|..                   :||..||||||||.:|::||:::
 Frog   292 NEMAQCQCPTDSMCWGLKQGYVT-------------------MFPFNIEYSLICATLLFIMWKNV 337

  Fly  1203 SRPQTPTPQRPDMISSPMKRSPHHYSVDCARAHKGLFVGILI---LVLTIISLIIFFVLISRPEF 1264
            .|       |..:.|.|.:   |.:.:      :|:..|.||   .:|..||:.:.:.:.:....
 Frog   338 GR-------REKLHSDPPR---HTFQL------RGIIYGPLIGGAALLVGISVFVQYQVEATSGM 386

  Fly  1265 VAMAVTEVTI-CELLIYGTATIATLVGMI------------------------------QIRHLQ 1298
            |::....:.. .:::|.....:.::.|:|                              :.::..
 Frog   387 VSILSYHMYYGYKMIILAPMIVCSVAGIIAHSLREKEKKGQKETGRSDQDWLHMEDVGSENKNTD 451

  Fly  1299 YDA--YRS--------------FSLDD---------------------------------ILLVG 1314
            |.:  |:|              |:||:                                 :|.|.
 Frog   452 YSSGQYQSSQGDEKIQGYSLAQFALDNEKEKLEHRQGNTTKKHNTHQGKMKNYTRKLDVTLLFVS 516

  Fly  1315 A--QTG-SFLYNIFTVIAGHFTLRSDDMLVPINALASIVQTACQTMFIL---------------- 1360
            |  |.| |:...|.||:...:|:.|  .|...|:|..|:|...|||||:
 Frog   517 AVGQLGISYFSIIATVVTTPWTMLS--ALNFSNSLLLILQYLSQTMFIIESMRSIHEEEKEKPGH 579

  Fly  1361 --DASRRQAVSPEH-------------LRKKPGREIVTFMLVVNLAMWAISTLEKSRAESHPIQL 1410
              ::.||.:|...|             |.::..:|:..|:::.|:..|.:...     .:||:.:
 Frog   580 HEESHRRMSVQEMHKAPPSCLDAGHLGLSRRVVKEMAMFLMICNIMCWILGAF-----GAHPLYM 639

  Fly  1411 N-----FYGLWAWTIITHVSMPLAIFYRFHSTVCLCEIWKRA 1447
            |     .||...|..|.::.:||::|||.||...|.|::..|
 Frog   640 NGLERQLYGSGIWLAILNIGLPLSVFYRMHSVGILLEVYLHA 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OtopLc	NP_001303575.1	Otopetrin	1015..1434	CDD:281218	106/552 (19%)
otop3	NP_001106584.1	Otopetrin	185..667	CDD:281218	105/550 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D243107at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9424
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X278
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010