DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and Chl1

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_038964701.1	Gene:	Chl1 / 89828	RGDID:	620122	Length:	1224	Species:	Rattus norvegicus

Alignment Length:	338	Identity:	79/338 - (23%)
Similarity:	127/338 - (37%)	Gaps:	59/338 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEF------TDVIENITVPAGRNVKLACSVKN 77
            |..:|:..:.|:.|.....|    ..|::....|:.      .....:.||..|..:.|.|..:.
  Rat   221 LTVNSLKHANDSSSSTEISN----QANSIKQRKPKLLLPPAQIGSASSKTVLKGDTLLLECFAEG 281

  Fly    78 LGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTV 142
            |.:.::.|            :.:.:..|:...|.:.|:|    .|.|.||..:|||.|.|..|.:
  Rat   282 LPTPQIEW------------SKLGSELPKGRATIEIHEK----TLKIENVSYQDRGNYRCTANNL 330

  Fly   143 TAKTQYGF-VKVVVPPNIDDALTSSDIIVREGDNVTLRCKAKGSPEPTIKWKRDDGNKIVINKTL 206
            ..|..:.| |.|..||.......|:  :...|.|..|.|:|:|.|:|||||:       |....:
  Rat   331 LGKASHDFHVIVEEPPRWKKKPQSA--VYSTGSNGILLCEAEGEPQPTIKWR-------VNGLPI 386

  Fly   207 EVHDLETD-----SLELERISRLHMGAYLCIASNGVPPSVSKRIKVS-VDFSPMVWIP----HQL 261
            |.|....|     .:....:...|...|.|.||| :..::.....:. ||..|::...    ::.
  Rat   387 ENHPFPGDVMFPREISFTNLQPNHTAVYQCEASN-IHGTILANANIDVVDVVPLIQTKNEENYET 450

  Fly   262 VGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATMRLTITNVQSSD 326
            |   :|::..|.|...|:|.:...|...::....|..:|       |.....|  |.|......|
  Rat   451 V---VGYSAFLHCEYFASPKATVVWEVADETHPLEGGRY-------HTHENGT--LEIERTTEED 503

  Fly   327 YGNYKCVAKNPRG 339
            .|:|.|...|..|
  Rat   504 AGSYSCWVDNTMG 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	25/96 (26%)
		Ig	69..139	CDD:143165	17/69 (25%)
		IG_like	165..249	CDD:214653	23/89 (26%)
		IGc2	172..237	CDD:197706	22/69 (32%)
		IG_like	267..348	CDD:214653	18/73 (25%)
		Ig	270..339	CDD:299845	16/68 (24%)
Chl1	XP_038964701.1	Ig	34..125	CDD:416386
		Ig strand A	34..38	CDD:409353
		Ig strand A'	43..47	CDD:409353
		Ig strand B	52..59	CDD:409353
		Ig strand C	65..70	CDD:409353
		Ig strand C'	73..75	CDD:409353
		Ig strand D	81..84	CDD:409353
		Ig strand E	89..93	CDD:409353
		Ig strand F	104..112	CDD:409353
		Ig strand G	115..125	CDD:409353
		IgI_2_L1-CAM_like	134..224	CDD:409432	1/2 (50%)
		Ig strand B	148..152	CDD:409432
		Ig strand C	162..166	CDD:409432
		Ig strand E	185..189	CDD:409432
		Ig strand F	200..205	CDD:409432
		Ig strand G	216..219	CDD:409432
		Ig	261..343	CDD:416386	24/97 (25%)
		Ig strand B	273..277	CDD:409353	1/3 (33%)
		Ig strand C	286..290	CDD:409353	1/15 (7%)
		Ig strand E	308..312	CDD:409353	2/7 (29%)
		Ig strand F	322..327	CDD:409353	2/4 (50%)
		Ig strand G	335..338	CDD:409353	0/2 (0%)
		Ig4_L1-NrCAM_like	347..434	CDD:409367	23/96 (24%)
		Ig strand B	363..367	CDD:409367	1/3 (33%)
		Ig strand C	376..380	CDD:409367	3/3 (100%)
		Ig strand E	399..403	CDD:409367	0/3 (0%)
		Ig strand F	413..418	CDD:409367	2/4 (50%)
		Ig strand G	426..429	CDD:409367	0/2 (0%)
		Ig	447..524	CDD:416386	19/82 (23%)
		Ig strand A'	447..451	CDD:409353	0/3 (0%)
		Ig strand B	454..463	CDD:409353	2/8 (25%)
		Ig strand C	469..474	CDD:409353	1/4 (25%)
		Ig strand C'	477..480	CDD:409353	0/2 (0%)
		Ig strand D	485..490	CDD:409353	2/11 (18%)
		Ig strand E	491..498	CDD:409353	3/8 (38%)
		Ig strand F	505..513	CDD:409353	3/7 (43%)
		Ig strand G	516..524	CDD:409353	1/1 (100%)
		Ig	528..627	CDD:416386
		Ig strand A	528..534	CDD:409353
		Ig strand A'	537..542	CDD:409353
		Ig strand B	545..553	CDD:409353
		Ig strand C	564..568	CDD:409353
		Ig strand D	583..586	CDD:409353
		Ig strand E	589..593	CDD:409353
		Ig strand F	602..609	CDD:409353
		Ig strand G	616..620	CDD:409353
		FN3	627..716	CDD:238020
		fn3	730..811	CDD:394996
		FN3	832..926	CDD:238020
		FN3	931..1026	CDD:238020
		Bravo_FIGEY	1120..1201	CDD:404722
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12231
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100