Protein Alignment DIP-epsilon and SIGLEC5

DIOPT Version :9

• Sequence 1: NP_001137799.1
• Gene: DIP-epsilon / 7354433
• FlyBaseID: FBgn0259714
• Length: 467
• Species: Drosophila melanogaster
• Sequence 2: XP_016882908.1
• Gene: SIGLEC5 / 8778
• HGNCID: 10874
• Length: 560
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 98/492 - (19%)
• Similarity: 167/492 - (33%)
• Gaps: 116/492 - (23%)

  Fly    40 GGSTLNNVISEDPEF-TDVIENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVH------ 97
            |||     :.|.|.: ..|.:::||..|..|.:.|      |:...|..:..|..|.|:
Human    12 GGS-----LQEKPVYELQVQKSVTVQEGLCVLVPC------SFSYPWRSWYSSPPLYVYWFRDGE 65

  Fly    98 -----NHVITRNP----------RISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQ 147
                 ..|.|.||          |..:..|...|:.:  |.|.:.:.||.|.|..::.. ....:
Human    66 IPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCS--LSIGDARMEDTGSYFFRVER-GRDVK 127

  Fly   148 YGFVKVVVPPNIDDALTSSDIIVRE----GDNVTLRCKAKGS----PEPTIKWKRDDGNKIVINK 204
            |.:.:..:...:...:...||...|    |....|.|...||    |..|..|   .||.:   .
Human   128 YSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW---TGNAL---S 186

  Fly   205 TLEVHDLETDSLELERISRLHMGAYLC-IASNGVPPSVSKRIKVSVDFSPM----------VWIP 258
            .|:.....:..|.|......|.....| :...|...:..:.::::|.::|.          :.|.
Human   187 PLDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITIFRNGIALEIL 251

  Fly   259 HQLVGIPI--GFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKATM-----R 316
            .....:|:  |..:.|.|...:||.:...|                  ..|.|:..||.     .
Human   252 QNTSYLPVLEGQALRLLCDAPSNPPAHLSW------------------FQGSPALNATPISNTGI 298

  Fly   317 LTITNVQSSDYGNYKCVAKNPRGDMDGNIKLYMSSPPTTQPPPTT---------TTLRRTTTTAA 372
            |.:..|:|::.|.:.|.|::|.|.:...:.|.:.|.|....|..:         .:.|.....:.
Human   299 LELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSL 363

  Fly   373 EIALDGYINTPLNGNG------IGIVGEGP--TNSVIASGKSSIKYLSNLNEIDKSKQKLTGSSP 429
            ...|:   ..||.||.      :.....||  .:|:|..|.     ||:..::......:.||..
Human   364 CWRLE---EKPLEGNSSQGSFKVNSSSAGPWANSSLILHGG-----LSSDLKVSCKAWNIYGSQS 420

  Fly   430 KGFDWSKGKSSGSHGNLMAS-----SWPLICCILALL 461
            ......:|:|:...|.:.|:     ...|:|..|.|:
Human   421 GSVLLLQGRSNLGTGVVPAALGGAGVMALLCICLCLI 457

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	24/116 (21%)
		Ig	69..139	CDD:143165	20/90 (22%)
		IG_like	165..249	CDD:214653	19/92 (21%)
		IGc2	172..237	CDD:197706	16/73 (22%)
		IG_like	267..348	CDD:214653	18/85 (21%)
		Ig	270..339	CDD:299845	16/73 (22%)
SIGLEC5	XP_016882908.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910