DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and Gpa33

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_067623.1	Gene:	Gpa33 / 59290	MGIID:	1891703	Length:	319	Species:	Mus musculus

Alignment Length:	263	Identity:	59/263 - (22%)
Similarity:	115/263 - (43%)	Gaps:	43/263 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GNAGNVGGSTLNNVISEDPEFTDVIENITVPA-GRNVKLACSVKNLGSYKVAWMHFEQSAILTVH 97
            |.||:|........::.|....:..::|...| ||:|.|.|:.....|.:..::.::: .:.:..
Mouse     3 GKAGSVVWMFCAIWVAADALTVETTQDILRAARGRSVTLPCTYNTYVSDREGFIQWDK-LLRSQT 66

  Fly    98 NHVITRN-------------PRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQIN-----TVTA 144
            ..|:|.|             .|:.|::|....:.:  :.|:.:..:|.|.|.|.::     .|.|
Mouse    67 ERVVTWNFVTKKYIYGNRYENRVRVSNDAELSNAS--ITIDQLTMDDNGTYECSVSLMSDQDVNA 129

  Fly   145 KTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRC-KAKGSPEPTIKWKRDDGNKIVINKTLEV 208
            |::...: |:|||:..|.....::::  |:|:.|.| .|:|||.|...||..:...   .:....
Mouse   130 KSRVRLL-VLVPPSKPDCSIQGEMVI--GNNIQLTCHSAEGSPSPQYSWKSYNAQN---QQRPLT 188

  Fly   209 HDLETDSLELERISRLHMGAYLCIASNGV------------PPSVSKRIKVSVDFSPMVWIPHQL 261
            ..:..:.|.|:.||....|.|:|.:||.|            |||::  |.:....:..|::...:
Mouse   189 QPVSGEPLLLKNISTETAGYYICTSSNDVGIESCNITVAPRPPSMN--IALYAGIAGSVFVALII 251

  Fly   262 VGI 264
            :|:
Mouse   252 IGV 254

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	23/114 (20%)
		Ig	69..139	CDD:143165	15/82 (18%)
		IG_like	165..249	CDD:214653	25/96 (26%)
		IGc2	172..237	CDD:197706	20/65 (31%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
Gpa33	NP_067623.1	V-set	31..138	CDD:284989	21/110 (19%)
		IG_like	31..137	CDD:214653	21/109 (19%)
		IG_like	151..226	CDD:214653	21/79 (27%)
		IGc2	154..218	CDD:197706	20/68 (29%)
		Shisa	<240..>262	CDD:290619	2/15 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	267..319
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910