DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and pigr

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	NP_001289179.1	Gene:	pigr / 566471	ZFINID:	ZDB-GENE-060503-327	Length:	335	Species:	Danio rerio

Alignment Length:	253	Identity:	52/253 - (20%)
Similarity:	95/253 - (37%)	Gaps:	53/253 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LIASSVALSTDTGSEGNAGNVGGSTLNNVISEDPEFTDVIE--NITVPAG------RNVKLACSV 75
            |:.:::.|....||......:|.             ..|:|  ::|||..      .|||..||.
Zfish     5 LLLTALVLGGLPGSHSTVTTIGD-------------VAVLEGGSVTVPCHYNPQYISNVKYWCSG 56

  Fly    76 KNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQIN 140
            :         |....|::....:.....|....||.........:.:::.|:.|:|.|.|.|.:.
Zfish    57 R---------MREFCSSLARTDDPESAPNGNRKVTIADDPTQHVFTVNMRNLTEDDSGWYWCGVE 112

  Fly   141 T----VTAKTQYGFVKVVVPPNIDDALTSSDIIVREGDNVTLRC-KAKGSPEPTIKWKRD----- 195
            .    |:..|...::.||...::.:.:.|::    ||.:|:::| .:|.......:|.|.
Zfish   113 LGGMWVSDSTASLYISVVQGMSVVNGMVSAE----EGKSVSVQCLYSKNLRSSEKRWCRSGNWNS 173

  Fly   196 ----DGNKIVINKTLEVHDLETD--SLELERISRLHMGAYLCIASN---GVPPSVSKR 244
                |.......|.:.:||.:..  ::.|:|:.....|.|.|.|..   .|..||::|
Zfish   174 CLLTDSEGTFSGKNVHIHDDKNSVFTVTLQRLEMRDSGWYWCGAGQQNVAVHVSVTRR 231

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	23/107 (21%)
		Ig	69..139	CDD:143165	15/69 (22%)
		IG_like	165..249	CDD:214653	22/95 (23%)
		IGc2	172..237	CDD:197706	17/79 (22%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
pigr	NP_001289179.1	IG_like	26..127	CDD:214653	24/122 (20%)
		Ig_pIgR	28..115	CDD:143193	21/95 (22%)
		Ig_pIgR	139..231	CDD:143193	21/95 (22%)
		IG_like	140..228	CDD:214653	19/91 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	40	1.000	Domainoid score	I12510
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000