DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DIP-epsilon and igsf5a

DIOPT Version :9

Sequence 1:	NP_001137799.1	Gene:	DIP-epsilon / 7354433	FlyBaseID:	FBgn0259714	Length:	467	Species:	Drosophila melanogaster
Sequence 2:	XP_021335124.1	Gene:	igsf5a / 561211	ZFINID:	ZDB-GENE-091204-182	Length:	331	Species:	Danio rerio

Alignment Length:	223	Identity:	46/223 - (20%)
Similarity:	74/223 - (33%)	Gaps:	48/223 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 ENITVPAGRNVKLACSVKNLGSYKVAWMHFEQSAILTVHNHVITRNPRISVTHDKHDKHRTWFLH 123
            :|..|..|.:.:..||...........::......:...:.|:....|.|.::.....:..|...
Zfish    23 QNAAVLQGSSAQFNCSSTQPPQIMTFMLNGRLVVTIMQTSGVLNSTDRFSASNFTTPGNYKWQFT 87

  Fly   124 INNVQEEDRGRYMCQI---NTVTAKTQY---GFVKVVVPPNIDDALTSSDIIVREGDNVT----- 177
            |:|||..|.|...||:   :.|||....   |.|::.                  |.|.|
Zfish    88 ISNVQRSDAGVVACQVLGGDAVTATLSVQDRGTVQIA------------------GGNQTKMLGV 134

  Fly   178 ---LRCKAKG-SPEPTIKWKRDDGNKIVINKTLEVHDLETDSLELERISRLHMGAYLCIA----- 233
               ..|.|.| .|||.:.|..:...:.....::....|...|..| .::........|:|
Zfish   135 QTQFSCLAAGWYPEPNMSWSVNGETQFCNKSSVTQGGLYNSSCTL-TLTASKNSTVQCLAAIPAL 198

  Fly   234 ----SNGVPPSVSKR-----IKVSVDFS 252
                ||.|..:|.|:     |.::|.||
Zfish   199 NTPDSNTVFLTVVKKDQTVLIAITVAFS 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	22/101 (22%)
		Ig	69..139	CDD:143165	13/69 (19%)
		IG_like	165..249	CDD:214653	21/106 (20%)
		IGc2	172..237	CDD:197706	17/82 (21%)
		IG_like	267..348	CDD:214653
		Ig	270..339	CDD:299845
igsf5a	XP_021335124.1	I-set	21..115	CDD:333254	20/91 (22%)
igsf5a	XP_021335124.1	Ig	<138..201	CDD:325142	12/63 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910